CVCDAP

Protein Analysis Tools for comparison of Two Cohorts

Heatmap : This tool identifies Differentially Expressed Genes (DEGs) between two cohorts (cohort 1 vs 2 using limma), and visualizes results as a heatmap with colors proportional to gene expression levels.

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Select two cohorts

Options for analysis

Options for plotting

Volcano Plot : This tool draws a volcano plot to enable quick visual identification of genes with statistical significance between two cohorts (cohort 1 vs 2 using limma) and magnitude of expression change.

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Select two cohorts

Options for analysis

Options for plotting

GSEA : This tool performs Gene Set Enrichment Analysis (GSEA) analysis to determine whether a priori defined set of proteins relating to the molecular mechanisms and biological processes, shows statistically significant and concordant differences between two cohorts. Down-regulated (NES < 0) and up-regulated (NES > 0) pathways in cohort 1 will be visualized as two barplots side by side (NES: normalized enrichment scores).

Help

Select two cohorts

Options for analysis

Options for plotting

Protein Analysis Tools for comparison of Two Cohorts

DEP analysis

Heatmap

Volcano Plot

GSEA

Box Plot