User-defined interaction

Interactors

Source AC: Q15831
Gene name: LKB1
Protein name: Serine/threonine-protein kinase STK11
Protein length: 433
Keywords: 3D-structure; Acetylation; Alternative splicing; Apoptosis; ATP-binding; Autophagy; Cell cycle; Cytoplasm; Differentiation; Disease variant; DNA damage; Kinase; Lipoprotein; Magnesium; Manganese; Membrane; Metal-binding; Methylation; Mitochondrion; Nucleotide-binding; Nucleus; Palmitate; Phosphoprotein; Prenylation; Reference proteome; Serine/threonine-protein kinase; Spermatogenesis; Transferase; Tumor suppressor;
GO: GO:0005737  [cytoplasm] ECO:0000314
GO:0005829  [cytosol] ECO:0000314
GO:0070062  [extracellular exosome] ECO:0007005
GO:0140535  [intracellular protein-containing complex] ECO:0000314
GO:0016020  [membrane] ECO:0000250
GO:0005739  [mitochondrion] ECO:0000314
GO:0005654  [nucleoplasm] ECO:0000314
GO:0005634  [nucleus] ECO:0000314
GO:1902554  [serine/threonine protein kinase complex] ECO:0000353
GO:0030018  [Z disc] ECO:0007669
GO:0005524  [ATP binding] ECO:0000314
GO:0030275  [LRR domain binding] ECO:0007669
GO:0000287  [magnesium ion binding] ECO:0000314
GO:0002039  [p53 binding] ECO:0000314
GO:0030295  [protein kinase activator activity] ECO:0000314
GO:0106310  [protein serine kinase activity] ECO:0007669
GO:0004674  [protein serine/threonine kinase activity] ECO:0000314
GO:0044877  [protein-containing complex binding] ECO:0007669
GO:0032147  [activation of protein kinase activity] ECO:0000314
GO:0043276  [anoikis] ECO:0000315
GO:0006914  [autophagy] ECO:0007669
GO:0007409  [axonogenesis] ECO:0007669
GO:0071493  [cellular response to UV-B] ECO:0000314
GO:0097484  [dendrite extension] ECO:0007669
GO:0006974  [DNA damage response] ECO:0000315
GO:0060767  [epithelial cell proliferation involved in prostate gland development] ECO:0007669
GO:0030010  [establishment of cell polarity] ECO:0000315
GO:0070314  [G1 to G0 transition] ECO:0000314
GO:0042593  [glucose homeostasis] ECO:0000250
GO:0051645  [Golgi localization] ECO:0007669
GO:0072332  [intrinsic apoptotic signaling pathway by p53 class mediator] ECO:0000314
GO:0090090  [negative regulation of canonical Wnt signaling pathway] ECO:0000315
GO:0030308  [negative regulation of cell growth] ECO:0000250
GO:0008285  [negative regulation of cell population proliferation] ECO:0000315
GO:0120163  [negative regulation of cold-induced thermogenesis] ECO:0000250
GO:0060770  [negative regulation of epithelial cell proliferation involved in prostate gland development] ECO:0007669
GO:1904262  [negative regulation of TORC1 signaling] ECO:0000315
GO:0018107  [peptidyl-threonine phosphorylation] ECO:0000314
GO:0010508  [positive regulation of autophagy] ECO:0000315
GO:0050772  [positive regulation of axonogenesis] ECO:0007669
GO:0045722  [positive regulation of gluconeogenesis] ECO:0007669
GO:1900182  [positive regulation of protein localization to nucleus] ECO:0007669
GO:0030511  [positive regulation of transforming growth factor beta receptor signaling pathway] ECO:0000315
GO:1901610  [positive regulation of vesicle transport along microtubule] ECO:0000315
GO:0045059  [positive thymic T cell selection] ECO:0007669
GO:0046777  [protein autophosphorylation] ECO:0000314
GO:0006470  [protein dephosphorylation] ECO:0000315
GO:0034504  [protein localization to nucleus] ECO:0007669
GO:0006468  [protein phosphorylation] ECO:0000314
GO:0051726  [regulation of cell cycle] ECO:0000304
GO:0001558  [regulation of cell growth] ECO:0000250
GO:0048814  [regulation of dendrite morphogenesis] ECO:0007669
GO:0051896  [regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction] ECO:0007669
GO:1901796  [regulation of signal transduction by p53 class mediator] ECO:0000304
GO:0030111  [regulation of Wnt signaling pathway] ECO:0000318
GO:0014823  [response to activity] ECO:0007669
GO:0033762  [response to glucagon] ECO:0007669
GO:0010212  [response to ionizing radiation] ECO:0000250
GO:0033993  [response to lipid] ECO:0007669
GO:0097066  [response to thyroid hormone] ECO:0007669
GO:0007165  [signal transduction] ECO:0000318
GO:0007283  [spermatogenesis] ECO:0007669
GO:0050852  [T cell receptor signaling pathway] ECO:0007669
GO:0001894  [tissue homeostasis] ECO:0007669
GO:0001944  [vasculature development] ECO:0000250
InterPro: IPR011009  [Kinase-like_dom_sf]
IPR039154  [LKB1_c]
IPR000719  [Prot_kinase_dom]
IPR017441  [Protein_kinase_ATP_BS]
IPR008271  [Ser/Thr_kinase_AS]
Organism: Homo sapiens

Source AC: Q8TDC3
Gene name: BRSK1
Protein name: Serine/threonine-protein kinase BRSK1
Protein length: 778
Keywords: Alternative splicing; ATP-binding; Cell cycle; Cell projection; Cytoplasm; Cytoplasmic vesicle; Cytoskeleton; DNA damage; Kinase; Magnesium; Metal-binding; Methylation; Neurogenesis; Nucleotide-binding; Nucleus; Phosphoprotein; Reference proteome; Serine/threonine-protein kinase; Synapse; Transferase;
GO: GO:0030054  [cell junction] ECO:0000314
GO:0005813  [centrosome] ECO:0000250
GO:0005737  [cytoplasm] ECO:0000314
GO:0150034  [distal axon] ECO:0000250
GO:0005654  [nucleoplasm] ECO:0000314
GO:0005634  [nucleus] ECO:0000314
GO:0048786  [presynaptic active zone] ECO:0000304
GO:0008021  [synaptic vesicle] ECO:0000250
GO:0005524  [ATP binding] ECO:0000305
GO:0043015  [gamma-tubulin binding] ECO:0000250
GO:0000287  [magnesium ion binding] ECO:0000314
GO:0019901  [protein kinase binding] ECO:0007669
GO:0106310  [protein serine kinase activity] ECO:0007669
GO:0004674  [protein serine/threonine kinase activity] ECO:0000314
GO:0048156  [tau protein binding] ECO:0000303
GO:0050321  [tau-protein kinase activity] ECO:0000314
GO:0008306  [associative learning] ECO:0000250
GO:0007409  [axonogenesis] ECO:0000250
GO:0051298  [centrosome duplication] ECO:0000250
GO:0006974  [DNA damage response] ECO:0000314
GO:0030010  [establishment of cell polarity] ECO:0000250
GO:0000086  [G2/M transition of mitotic cell cycle] ECO:0000314
GO:0035556  [intracellular signal transduction] ECO:0000318
GO:0090176  [microtubule cytoskeleton organization involved in establishment of planar polarity] ECO:0000250
GO:0007095  [mitotic G2 DNA damage checkpoint signaling] ECO:0000314
GO:0030182  [neuron differentiation] ECO:0000250
GO:0007269  [neurotransmitter secretion] ECO:0000250
GO:0018105  [peptidyl-serine phosphorylation] ECO:0000314
GO:0006468  [protein phosphorylation] ECO:0000314
GO:0050770  [regulation of axonogenesis] ECO:0000250
GO:0010975  [regulation of neuron projection development] ECO:0000250
GO:0048167  [regulation of synaptic plasticity] ECO:0000250
GO:2000807  [regulation of synaptic vesicle clustering] ECO:0000304
GO:0009411  [response to UV] ECO:0000314
GO:0099504  [synaptic vesicle cycle] ECO:0000250
InterPro: IPR048622  [BRSK1_2-like_UBA]
IPR011009  [Kinase-like_dom_sf]
IPR000719  [Prot_kinase_dom]
IPR017441  [Protein_kinase_ATP_BS]
IPR008271  [Ser/Thr_kinase_AS]
IPR015940  [UBA]
Organism: Homo sapiens

Public comments

Comment 1 from: makelab members
Believe this interaction: Yes
Comment: PMID: 14976552