Note:
1) The releases before December 7, 2009 contain genetic interactions mostly from BioGRID. We are sorry for inconveniences.
2) The download files of Feb 25, 2011 and after only contain protein-protein interactions, of which both partners are from the same species.

Last update: May 21, 2014

Organisms Binary interactions* Complexes**
Homo sapiens 166,776   (download: MITAB format   SIF format) 5211
Saccharomyces cerevisiae 94,414   (download: MITAB format   SIF format) 6159
Caenorhabditis elegans 14,829   (download: MITAB format   SIF format) 54
Drosophila melanogaster 52,280   (download: MITAB format   SIF format) 395
Mus musculus 13,865    (download: MITAB format   SIF format) 680
Rattus norvegicus 3,804    (download: MITAB format   SIF format) 159
Arabidopsis thaliana 19,962    (download: MITAB format   SIF format) 311
Original databaes (version)
IntAct April 21, 2014
BioGRID 3.2.112 (May 1, 2014)
MINT Dec 21, 2010
DIP June 14, 2010
HPRD April 13, 2010
MIPS/MPact Oct 1, 2008
* Number of interactions: The number is the sum of self-interaction and binary interaction that all participating proteins have UniProt Accession Number.
** Number of complexes: The number is the sum of complexes that all participating proteins have UniProt Accession Number.
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