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Network FourFactors4iPScells (419 proteins, 418 interactions, 33 user-defined )

Query proteins are Oct4, Sox2, Klf4 and Myc, which are four factors needed for the generation of induced pluripotent stem (iPS) cells.

Interactors (10) of the query protein: POU5F1 (Q01860)

Interactors (5) of the query protein: SOX2 (P48431)

Interactors (4) of the query protein: KLF4 (O43474)

Interactors (400) of the query protein: MYC (P01106)

Interactors(10) of the protein: POU5F1 (Q01860 )



Interaction detail UniProt AC Gene name Protein name Protein length Keywords
1 P10275 AR Androgen receptor 920 3D-structure; Activator; Alternative splicing; Cytoplasm; DNA-binding; Disease mutation; Isopeptide bond; Lipid-binding; Lipoprotein; Metal-binding; Neurodegeneration; Nucleus; Palmitate; Phosphoprotein; Polymorphism; Pseudohermaphroditism; Receptor; Reference proteome; Steroid-binding; Transcription; Transcription regulation; Triplet repeat expansion; Ubl conjugation; Zinc; Zinc-finger
1 P15036 ETS2 Protein C-ets-2 469 3D-structure; DNA-binding; Nucleus; Phosphoprotein; Proto-oncogene; Reference proteome; Transcription; Transcription regulation
User defined Q01844 EWSR1 RNA-binding protein EWS 656 3D-structure; Acetylation; Alternative splicing; Calmodulin-binding; Cell membrane; Chromosomal rearrangement; Cytoplasm; Direct protein sequencing; Membrane; Metal-binding; Methylation; Nucleus; Phosphoprotein; Proto-oncogene; RNA-binding; Reference proteome; Repeat; Repressor; Transcription; Transcription regulation; Zinc; Zinc-finger
1 Q9UJU5 FOXD3 Forkhead box protein D3 478 Activator; DNA-binding; Developmental protein; Nucleus; Reference proteome; Repressor; Transcription; Transcription regulation
1 P09429 HMGB1 High mobility group protein B1 215 3D-structure; ADP-ribosylation; Acetylation; Adaptive immunity; Autophagy; Cell membrane; Chemotaxis; Chromosome; Cytoplasm; DNA damage; DNA recombination; DNA repair; DNA-binding; Direct protein sequencing; Disulfide bond; Endosome; Host-virus interaction; Immunity; Inflammatory response; Innate immunity; Membrane; Nucleus; Oxidation; Phosphoprotein; Polymorphism; Reference proteome; Repeat; Secreted
1 P26583 HMGB2 High mobility group protein B2 209 Acetylation; Chemotaxis; Chromosome; Cytoplasm; Disulfide bond; DNA recombination; DNA-binding; Immunity; Inflammatory response; Innate immunity; Nucleus; Oxidation; Phosphoprotein; Reference proteome; Repeat; Secreted; Transcription; Transcription regulation;
2 P51948 MNAT1 CDK-activating kinase assembly factor MAT1 309 3D-structure; Acetylation; Alternative splicing; Cell cycle; Direct protein sequencing; Metal-binding; Nucleus; Phosphoprotein; Polymorphism; Reference proteome; Transcription; Transcription regulation; Zinc; Zinc-finger
4 P48431 SOX2 Transcription factor SOX-2 317 3D-structure; Activator; DNA-binding; Developmental protein; Disease mutation; Isopeptide bond; Microphthalmia; Nucleus; Phosphoprotein; Reference proteome; Transcription; Transcription regulation; Ubl conjugation
1 P56693 SOX10 Transcription factor SOX-10 466 Activator; Alternative splicing; Cytoplasm; DNA-binding; Deafness; Disease mutation; Hirschsprung disease; Kallmann syndrome; Membrane; Mitochondrion; Mitochondrion outer membrane; Nucleus; Phosphoprotein; Reference proteome; Transcription; Transcription regulation; Waardenburg syndrome
1 P57073 SOX8 Transcription factor SOX-8 446 DNA-binding; Nucleus; Reference proteome; Transcription; Transcription regulation


Interactors(5) of the protein: SOX2 (P48431 )



Interaction detail UniProt AC Gene name Protein name Protein length Keywords
1 P08620 FGF4 Fibroblast growth factor 4 206 3D-structure; Alternative splicing; Developmental protein; Differentiation; Growth factor; Heparin-binding; Mitogen; Proto-oncogene; Reference proteome; Secreted; Signal
1 Q13285 NR5A1 Steroidogenic factor 1 461 3D-structure; Acetylation; Activator; DNA-binding; Disease mutation; Isopeptide bond; Lipid-binding; Metal-binding; Nucleus; Phosphoprotein; Polymorphism; Premature ovarian failure; Receptor; Reference proteome; Transcription; Transcription regulation; Ubl conjugation; Zinc; Zinc-finger
1 P26367 PAX6 Paired box protein Pax-6 422 3D-structure; Alternative splicing; DNA-binding; Developmental protein; Differentiation; Disease mutation; Homeobox; Nucleus; Paired box; Peters anomaly; Reference proteome; Repressor; Transcription; Transcription regulation; Ubl conjugation
2 P14859 POU2F1 POU domain, class 2, transcription factor 1 743 3D-structure; Activator; Alternative splicing; DNA-binding; Homeobox; Nucleus; Phosphoprotein; Polymorphism; Reference proteome; Transcription; Transcription regulation
4 Q01860 POU5F1 POU domain, class 5, transcription factor 1 360 Alternative splicing; Cytoplasm; DNA-binding; Developmental protein; Homeobox; Isopeptide bond; Nucleus; Phosphoprotein; Polymorphism; Reference proteome; Transcription; Transcription regulation; Ubl conjugation


Interactors(4) of the protein: KLF4 (O43474 )



Interaction detail UniProt AC Gene name Protein name Protein length Keywords
1 Q92793 CREBBP CREB-binding protein 2442 3D-structure; Acetylation; Activator; Acyltransferase; Alternative splicing; Biological rhythms; Bromodomain; Chromosomal rearrangement; Cytoplasm; Disease mutation; Host-virus interaction; Isopeptide bond; Mental retardation; Metal-binding; Methylation; Nucleus; Phosphoprotein; Polymorphism; Reference proteome; Repeat; Transcription; Transcription regulation; Transferase; Ubl conjugation; Zinc; Zinc-finger
2 Q99612 KLF6 Krueppel-like factor 6 283 Activator; Alternative splicing; DNA-binding; Metal-binding; Nucleus; Polymorphism; Reference proteome; Repeat; Transcription; Transcription regulation; Zinc; Zinc-finger
1 P08047 SP1 Transcription factor Sp1 785 3D-structure; Acetylation; Activator; Alternative splicing; Biological rhythms; Cytoplasm; DNA-binding; Direct protein sequencing; Glycoprotein; Host-virus interaction; Isopeptide bond; Metal-binding; Nucleus; Phosphoprotein; Polymorphism; Reference proteome; Repeat; Repressor; Transcription; Transcription regulation; Ubl conjugation; Zinc; Zinc-finger
1 P04637 p53 Cellular tumor antigen p53 393 3D-structure; Acetylation; Activator; Alternative promoter usage; Alternative splicing; Apoptosis; Biological rhythms; Cell cycle; Cytoplasm; Cytoskeleton; DNA-binding; Direct protein sequencing; Disease mutation; Endoplasmic reticulum; Glycoprotein; Host-virus interaction; Isopeptide bond; Li-Fraumeni syndrome; Metal-binding; Methylation; Mitochondrion; Necrosis; Nucleus; Phosphoprotein; Polymorphism; Reference proteome; Repressor; Transcription; Transcription regulation; Tumor suppressor; Ubl conjugation; Zinc


Interactors(400) of the protein: MYC (P01106 )



Interaction detail UniProt AC Gene name Protein name Protein length Keywords
1 genbank_protein_gi:11038639 11038639 11038639
User defined 11641423 11641423 11641423
1 genbank_protein_gi:14285370 14285370 14285370
User defined 31083367 31083367 31083367
1 genbank_protein_gi:4753161 4753161 4753161
1 genbank_protein_gi:4757996 4757996 4757996
User defined 51467195 51467195 51467195
1 genbank_protein_gi:51467589 51467589 51467589
1 genbank_protein_gi:51471344 51471344 51471344
1 genbank_protein_gi:51475741 51475741 51475741
User defined A0A4Z0 A0A4Z0 A0A4Z0
2 Q9UDR5 AASS Alpha-aminoadipic semialdehyde synthase, mitochondrial 926 3D-structure; Acetylation; Mitochondrion; Multifunctional enzyme; NAD; NADP; Oxidoreductase; Reference proteome; Transit peptide
1 O75027 ABCB7 ATP-binding cassette sub-family B member 7, mitochondrial 752 ATP-binding; Acetylation; Alternative splicing; Disease mutation; Membrane; Mitochondrion; Mitochondrion inner membrane; Nucleotide-binding; Phosphoprotein; Polymorphism; Reference proteome; Transit peptide; Transmembrane; Transmembrane helix; Transport
2 Q13085 ACACA Acetyl-CoA carboxylase 1 2346 3D-structure; Acetylation; Allosteric enzyme; Alternative promoter usage; ATP-binding; Biotin; Cytoplasm; Direct protein sequencing; Fatty acid biosynthesis; Fatty acid metabolism; Ligase; Lipid biosynthesis; Lipid metabolism; Magnesium; Manganese; Metal-binding; Multifunctional enzyme; Nucleotide-binding; Phosphoprotein; Reference proteome;
2 O14734 ACOT8 Acyl-coenzyme A thioesterase 8 319 Fatty acid metabolism; Host-virus interaction; Hydrolase; Lipid metabolism; Peroxisome; Peroxisome biogenesis; Reference proteome; Serine esterase
1 P60709 ACTB Actin, cytoplasmic 1 375 3D-structure; ATP-binding; Acetylation; Cytoplasm; Cytoskeleton; Deafness; Direct protein sequencing; Disease mutation; Dystonia; Isopeptide bond; Mental retardation; Methylation; Nucleotide-binding; Nucleus; Oxidation; Polymorphism; Reference proteome; Ubl conjugation
2 O96019 ACTL6A Actin-like protein 6A 429 3D-structure; Acetylation; Activator; Alternative splicing; Chromatin regulator; DNA damage; DNA recombination; DNA repair; Direct protein sequencing; Disease mutation; Growth regulation; Isopeptide bond; Mental retardation; Neurogenesis; Nucleus; Phosphoprotein; Reference proteome; Transcription; Transcription regulation; Ubl conjugation
3 O43823 AKAP8 A-kinase anchor protein 8 692 Cytoplasm; DNA-binding; Immunity; Innate immunity; Isopeptide bond; Metal-binding; Methylation; Nucleus; Phosphoprotein; Polymorphism; Protein transport; Reference proteome; Repeat; Transcription; Transcription regulation; Transport; Ubl conjugation; Zinc; Zinc-finger
2 Q9ULX6 AKAP8L A-kinase anchor protein 8-like 646 Acetylation; Alternative splicing; Cytoplasm; Host-virus interaction; Metal-binding; Methylation; mRNA processing; mRNA splicing; Nucleus; Phosphoprotein; Reference proteome; Repeat; Transcription; Transcription regulation; Zinc; Zinc-finger;
2 P54886 ALDH18A1 Delta-1-pyrroline-5-carboxylate synthase 795 3D-structure; ATP-binding; Alternative splicing; Amino-acid biosynthesis; Disease mutation; Hereditary spastic paraplegia; Kinase; Membrane; Mental retardation; Mitochondrion; Mitochondrion inner membrane; Multifunctional enzyme; NADP; Neurodegeneration; Nucleotide-binding; Oxidoreductase; Polymorphism; Proline biosynthesis; Reference proteome; Transferase
2 P30837 ALDH1B1 Aldehyde dehydrogenase X, mitochondrial 517 Acetylation; Mitochondrion; NAD; Oxidoreductase; Polymorphism; Reference proteome; Transit peptide
1 O95782 AP2A1 AP-2 complex subunit alpha-1 977 Alternative splicing; Cell membrane; Coated pit; Endocytosis; Membrane; Phosphoprotein; Polymorphism; Protein transport; Reference proteome; Transport
1 O14617 AP3D1 AP-3 complex subunit delta-1 1153 3D-structure; Acetylation; Albinism; Alternative splicing; Coiled coil; Cytoplasm; Golgi apparatus; Hermansky-Pudlak syndrome; Membrane; Phosphoprotein; Polymorphism; Protein transport; Reference proteome; Repeat; Transport
1 P48444 ARCN1 Coatomer subunit delta 511 Acetylation; Alternative splicing; Cytoplasm; Cytoplasmic vesicle; Dwarfism; ER-Golgi transport; Golgi apparatus; Membrane; Phosphoprotein; Polymorphism; Protein transport; Reference proteome; Transport
1 P84077 ARF1 ADP-ribosylation factor 1 181 3D-structure; Acetylation; Cell junction; Cytoplasm; Direct protein sequencing; Disease mutation; ER-Golgi transport; GTP-binding; Golgi apparatus; Lipoprotein; Membrane; Myristate; Nucleotide-binding; Protein transport; Reference proteome; Synapse; Synaptosome; Transport
2 P18085 ARF4 ADP-ribosylation factor 4 180 3D-structure; ER-Golgi transport; GTP-binding; Golgi apparatus; Lipoprotein; Membrane; Myristate; Nucleotide-binding; Phosphoprotein; Polymorphism; Protein transport; Reference proteome; Transport
2 Q92974 ARHGEF2 Rho guanine nucleotide exchange factor 2 986 3D-structure; Acetylation; Alternative splicing; Cell cycle; Cell division; Cell junction; Cell membrane; Cell projection; Coiled coil; Cytoplasm; Cytoplasmic vesicle; Cytoskeleton; Developmental protein; Differentiation; Golgi apparatus; Guanine-nucleotide releasing factor; Immunity; Innate immunity; Membrane; Mental retardation; Metal-binding; Microtubule; Mitosis; Neurogenesis; Phosphoprotein; Reference proteome; Tight junction; Zinc; Zinc-finger
2 P40616 ARL1 ADP-ribosylation factor-like protein 1 181 3D-structure; Alternative splicing; GTP-binding; Golgi apparatus; Lipoprotein; Magnesium; Membrane; Metal-binding; Myristate; Nucleotide-binding; Reference proteome
1 Q6NXE6 ARMC6 Armadillo repeat-containing protein 6 501 Alternative splicing; Phosphoprotein; Reference proteome; Repeat
2 P00966 ASS1 Argininosuccinate synthase 412 3D-structure; ATP-binding; Acetylation; Amino-acid biosynthesis; Arginine biosynthesis; Cytoplasm; Direct protein sequencing; Disease mutation; Ligase; Nucleotide-binding; Phosphoprotein; Polymorphism; Reference proteome; Urea cycle
1 P05023 ATP1A1 Sodium/potassium-transporting ATPase subunit alpha-1 1023 3D-structure; Acetylation; Alternative splicing; ATP-binding; Cell membrane; Cell projection; Charcot-Marie-Tooth disease; Direct protein sequencing; Epilepsy; Intellectual disability; Ion transport; Magnesium; Membrane; Metal-binding; Neurodegeneration; Neuropathy; Nucleotide-binding; Phosphoprotein; Potassium; Potassium transport; Primary hypomagnesemia; Reference proteome; Sodium; Sodium transport; Sodium/potassium transport; Translocase; Transmembrane; Transmembrane helix; Transport;
2 P16615 ATP2A2 Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 1042 3D-structure; ATP-binding; Alternative splicing; Calcium; Calcium transport; Disease mutation; Disulfide bond; Endoplasmic reticulum; Epilepsy; Ion transport; Magnesium; Membrane; Metal-binding; Nitration; Nucleotide-binding; Phosphoprotein; Reference proteome; Sarcoplasmic reticulum; Translocase; Transmembrane; Transmembrane helix; Transport
3 P36542 ATP5F1C ATP synthase subunit gamma, mitochondrial 298 ATP synthesis; Acetylation; Alternative splicing; CF(1); Direct protein sequencing; Hydrogen ion transport; Ion transport; Membrane; Mitochondrion; Mitochondrion inner membrane; Phosphoprotein; Reference proteome; Transit peptide; Transport
3 P56134 ATP5MF ATP synthase subunit f, mitochondrial 94 ATP synthesis; Acetylation; Alternative splicing; CF(0); Hydrogen ion transport; Ion transport; Membrane; Mitochondrion; Mitochondrion inner membrane; Phosphoprotein; Reference proteome; Transmembrane; Transmembrane helix; Transport
1 Q9UI12 ATP6V1H V-type proton ATPase subunit H 483 Alternative splicing; Host-virus interaction; Hydrogen ion transport; Ion transport; Phosphoprotein; Reference proteome; Transport
User defined B3KNM8 B3KNM8 B3KNM8
1 P10415 BCL2 Apoptosis regulator Bcl-2 239 3D-structure; Alternative splicing; Apoptosis; Chromosomal rearrangement; Disease mutation; Endoplasmic reticulum; Membrane; Mitochondrion; Mitochondrion outer membrane; Nucleus; Phosphoprotein; Polymorphism; Proto-oncogene; Reference proteome; Transmembrane; Transmembrane helix; Ubl conjugation
2 P11274 BCR Breakpoint cluster region protein 1271 3D-structure; ATP-binding; Acetylation; Alternative splicing; Cell junction; Cell projection; Chromosomal rearrangement; GTPase activation; Guanine-nucleotide releasing factor; Kinase; Methylation; Nucleotide-binding; Phosphoprotein; Polymorphism; Proto-oncogene; Reference proteome; Serine/threonine-protein kinase; Synapse; Transferase
1 O00499 BIN1 Myc box-dependent-interacting protein 1 593 3D-structure; Acetylation; Alternative splicing; Cell membrane; Coiled coil; Cytoplasm; Developmental protein; Differentiation; Disease mutation; Endocytosis; Endosome; Host-virus interaction; Membrane; Nucleus; Phosphoprotein; Reference proteome; SH3 domain
1 P78537 BLOC1S1 Biogenesis of lysosome-related organelles complex 1 subunit 1 153 Alternative initiation; Coiled coil; Cytoplasm; Lysosome; Membrane; Mitochondrion; Reference proteome
1 P38398 BRCA1 Breast cancer type 1 susceptibility protein 1863 3D-structure; Acetylation; Activator; Alternative initiation; Alternative splicing; Cell cycle; Chromosome; Cytoplasm; DNA damage; DNA recombination; DNA repair; DNA-binding; Direct protein sequencing; Disease mutation; Fanconi anemia; Fatty acid biosynthesis; Fatty acid metabolism; Isopeptide bond; Lipid biosynthesis; Lipid metabolism; Metal-binding; Nucleus; Phosphoprotein; Polymorphism; Reference proteome; Repeat; Transcription; Transcription regulation; Transferase; Tumor suppressor; Ubl conjugation; Ubl conjugation pathway; Zinc; Zinc-finger
1 O14981 BTAF1 TATA-binding protein-associated factor 172 1849 ATP-binding; Alternative splicing; DNA-binding; Direct protein sequencing; Helicase; Hydrolase; Nucleotide-binding; Nucleus; Phosphoprotein; Reference proteome; Repeat
2 Q07021 C1QBP Complement component 1 Q subcomponent-binding protein, mitochondrial 282 3D-structure; Acetylation; Adaptive immunity; Apoptosis; Cell membrane; Complement pathway; Cytoplasm; Direct protein sequencing; Disease mutation; Host-virus interaction; Immunity; Innate immunity; Membrane; Mitochondrion; Nucleus; Phosphoprotein; Primary mitochondrial disease; Reference proteome; Ribosome biogenesis; Secreted; Transcription; Transcription regulation; Transit peptide; mRNA processing; mRNA splicing
5 Q8N163 CCAR2 Cell cycle and apoptosis regulator protein 2 923 Acetylation; Activator; Alternative splicing; Apoptosis; Biological rhythms; Cell cycle; Coiled coil; Cytoplasm; DNA damage; Isopeptide bond; Metalloenzyme inhibitor; Methylation; Nucleus; Phosphoprotein; Reference proteome; Repressor; Transcription; Transcription regulation; Tumor suppressor; Ubl conjugation; Wnt signaling pathway; mRNA processing; mRNA splicing
2 O00622 CCN1 CCN family member 1 381 3D-structure; Cell adhesion; Chemotaxis; Disulfide bond; Growth factor binding; Heparin-binding; Phosphoprotein; Polymorphism; Reference proteome; Secreted; Signal
1 O60563 CCNT1 Cyclin-T1 726 3D-structure; Acetylation; Alternative splicing; Cell cycle; Cell division; Coiled coil; Cyclin; Direct protein sequencing; Host-virus interaction; Isopeptide bond; Nucleus; Phosphoprotein; Polymorphism; Reference proteome; Transcription; Transcription regulation; Ubl conjugation
2 P78371 CCT2 T-complex protein 1 subunit beta 535 3D-structure; ATP-binding; Acetylation; Alternative splicing; Chaperone; Cytoplasm; Direct protein sequencing; Isopeptide bond; Nucleotide-binding; Phosphoprotein; Reference proteome; Ubl conjugation
2 P49368 CCT3 T-complex protein 1 subunit gamma 545 3D-structure; ATP-binding; Acetylation; Alternative splicing; Chaperone; Cytoplasm; Direct protein sequencing; Disulfide bond; Isopeptide bond; Nucleotide-binding; Phosphoprotein; Polymorphism; Reference proteome; Ubl conjugation
2 P50991 CCT4 T-complex protein 1 subunit delta 539 3D-structure; ATP-binding; Acetylation; Alternative splicing; Cell projection; Chaperone; Cytoplasm; Cytoskeleton; Direct protein sequencing; Methylation; Nucleotide-binding; Phosphoprotein; Polymorphism; Reference proteome
2 P48643 CCT5 T-complex protein 1 subunit epsilon 541 3D-structure; ATP-binding; Acetylation; Alternative splicing; Chaperone; Cytoplasm; Cytoskeleton; Direct protein sequencing; Disease mutation; Isopeptide bond; Neuropathy; Nucleotide-binding; Phosphoprotein; Polymorphism; Reference proteome; Ubl conjugation
2 P40227 CCT6A T-complex protein 1 subunit zeta 531 3D-structure; ATP-binding; Acetylation; Alternative splicing; Chaperone; Cytoplasm; Direct protein sequencing; Isopeptide bond; Nucleotide-binding; Phosphoprotein; Polymorphism; Reference proteome; Ubl conjugation
2 P50990 CCT8 T-complex protein 1 subunit theta 548 3D-structure; ATP-binding; Acetylation; Alternative splicing; Cell projection; Chaperone; Cilium; Cytoplasm; Cytoskeleton; Direct protein sequencing; Isopeptide bond; Nucleotide-binding; Phosphoprotein; Polymorphism; Reference proteome; Ubl conjugation
1 P30203 CD6 T-cell differentiation antigen CD6 668 3D-structure; Adaptive immunity; Alternative splicing; Cell adhesion; Cell membrane; Disulfide bond; Glycoprotein; Immunity; Innate immunity; Membrane; Phosphoprotein; Polymorphism; Reference proteome; Repeat; Secreted; Signal; Transmembrane; Transmembrane helix
1 Q99741 CDC6 Cell division control protein 6 homolog 560 3D-structure; ATP-binding; Cell cycle; Cell division; Cytoplasm; DNA replication; Disease mutation; Dwarfism; Mitosis; Nucleotide-binding; Nucleus; Phosphoprotein; Polymorphism; Reference proteome
4 P06493 CDK1 Cyclin-dependent kinase 1 297 3D-structure; ATP-binding; Acetylation; Alternative splicing; Apoptosis; Biological rhythms; Cell cycle; Cell division; Cytoplasm; Cytoskeleton; Host cell receptor for virus entry; Host-virus interaction; Isopeptide bond; Kinase; Mitochondrion; Mitosis; Nucleotide-binding; Nucleus; Phosphoprotein; Receptor; Reference proteome; Serine/threonine-protein kinase; Transferase; Ubl conjugation
1 P50750 CDK9 Cyclin-dependent kinase 9 372 3D-structure; ATP-binding; Acetylation; Alternative splicing; Cytoplasm; DNA damage; DNA repair; Kinase; Nucleotide-binding; Nucleus; Phosphoprotein; Polymorphism; Reference proteome; Serine/threonine-protein kinase; Transcription; Transcription regulation; Transferase; Ubl conjugation
1 Q8N726 CDKN2A Tumor suppressor ARF 132 Alternative splicing; Apoptosis; Cell cycle; DNA-binding; Mitochondrion; Nucleus; Polymorphism; Reference proteome; Transcription; Transcription regulation; Tumor suppressor; Ubl conjugation; Ubl conjugation pathway; rRNA processing
1 P49715 CEBPA CCAAT/enhancer-binding protein alpha 358 3D-structure; Acetylation; Activator; Alternative initiation; DNA-binding; Developmental protein; Disease mutation; Host-virus interaction; Isopeptide bond; Nucleus; Phosphoprotein; Reference proteome; Transcription; Transcription regulation; Ubl conjugation
1 P17676 CEBPB CCAAT/enhancer-binding protein beta 345 3D-structure; Acetylation; Activator; Alternative initiation; Cytoplasm; DNA-binding; Differentiation; Glycoprotein; Isopeptide bond; Methylation; Nucleus; Phosphoprotein; Polymorphism; Reference proteome; Transcription; Transcription regulation; Ubl conjugation
1 Q03701 CEBPZ CCAAT/enhancer-binding protein zeta 1054 Acetylation; Activator; Nucleus; Phosphoprotein; Polymorphism; Reference proteome; Transcription; Transcription regulation
2 Q9Y6K0 CEPT1 Choline/ethanolaminephosphotransferase 1 416 Endoplasmic reticulum; Glycoprotein; Lipid biosynthesis; Lipid metabolism; Magnesium; Manganese; Membrane; Metal-binding; Nucleus; Phospholipid biosynthesis; Phospholipid metabolism; Phosphoprotein; Reference proteome; Transferase; Transmembrane; Transmembrane helix
3 Q14839 CHD4 Chromodomain-helicase-DNA-binding protein 4 1912 3D-structure; ATP-binding; Acetylation; Alternative splicing; Chromatin regulator; Cytoplasm; Cytoskeleton; DNA-binding; Disease mutation; Helicase; Hydrolase; Isopeptide bond; Mental retardation; Metal-binding; Nucleotide-binding; Nucleus; Phosphoprotein; Polymorphism; Reference proteome; Repeat; Transcription; Transcription regulation; Ubl conjugation; Zinc; Zinc-finger
1 Q8TDI0 CHD5 Chromodomain-helicase-DNA-binding protein 5 1954 3D-structure; ATP-binding; Chromatin regulator; DNA-binding; Differentiation; Helicase; Hydrolase; Metal-binding; Methylation; Neurogenesis; Nucleotide-binding; Nucleus; Phosphoprotein; Polymorphism; Reference proteome; Repeat; Spermatogenesis; Transcription; Transcription regulation; Tumor suppressor; Zinc; Zinc-finger
2 Q8WVB6 CHTF18 Chromosome transmission fidelity protein 18 homolog 975 ATP-binding; Alternative splicing; Cell cycle; DNA replication; DNA-binding; Nucleotide-binding; Nucleus; Phosphoprotein; Polymorphism; Reference proteome
1 Q8TCG1 CIP2A Protein CIP2A 905 3D-structure; Acetylation; Alternative splicing; Coiled coil; Cytoplasm; Membrane; Phosphoprotein; Polymorphism; Reference proteome; Transmembrane; Transmembrane helix
1 P35606 COPB2 Coatomer subunit beta' 906 Acetylation; Alternative splicing; Coiled coil; Cytoplasm; Cytoplasmic vesicle; Direct protein sequencing; Disease mutation; ER-Golgi transport; Golgi apparatus; Membrane; Phosphoprotein; Primary microcephaly; Protein transport; Reference proteome; Repeat; Transport; WD repeat
2 Q9Y678 COPG1 Coatomer subunit gamma-1 874 3D-structure; Cytoplasm; Cytoplasmic vesicle; ER-Golgi transport; Golgi apparatus; Membrane; Phosphoprotein; Polymorphism; Protein transport; Reference proteome; Repeat; Transport
2 Q9UBF2 COPG2 Coatomer subunit gamma-2 871 Alternative splicing; Cytoplasm; Cytoplasmic vesicle; ER-Golgi transport; Golgi apparatus; Membrane; Phosphoprotein; Polymorphism; Protein transport; Reference proteome; Repeat; Transport
1 Q10570 CPSF1 Cleavage and polyadenylation specificity factor subunit 1 1443 3D-structure; Nucleus; Phosphoprotein; RNA-binding; Reference proteome; mRNA processing
1 Q92793 CREBBP CREB-binding protein 2442 3D-structure; Acetylation; Activator; Acyltransferase; Alternative splicing; Biological rhythms; Bromodomain; Chromosomal rearrangement; Cytoplasm; Disease mutation; Host-virus interaction; Isopeptide bond; Mental retardation; Metal-binding; Methylation; Nucleus; Phosphoprotein; Polymorphism; Reference proteome; Repeat; Transcription; Transcription regulation; Transferase; Ubl conjugation; Zinc; Zinc-finger
2 P55060 CSE1L Exportin-2 971 Acetylation; Alternative splicing; Cytoplasm; Direct protein sequencing; Nucleus; Phosphoprotein; Protein transport; Reference proteome; Transport;
1 P68400 CSNK2A1 Casein kinase II subunit alpha 391 3D-structure; ATP-binding; Alternative splicing; Apoptosis; Biological rhythms; Cell cycle; Disease mutation; Kinase; Mental retardation; Nucleotide-binding; Nucleus; Phosphoprotein; Polymorphism; Reference proteome; Serine/threonine-protein kinase; Transcription; Transcription regulation; Transferase; Wnt signaling pathway
1 P19784 CSNK2A2 Casein kinase II subunit alpha' 350 3D-structure; ATP-binding; Acetylation; Apoptosis; Cell cycle; Kinase; Nucleotide-binding; Phosphoprotein; Polymorphism; Reference proteome; Serine/threonine-protein kinase; Transcription; Transcription regulation; Transferase; Wnt signaling pathway
2 P17812 CTPS1 CTP synthase 1 591 3D-structure; ATP-binding; Acetylation; Alternative splicing; Cytoplasm; Glutamine amidotransferase; Immunity; Ligase; Nucleotide-binding; Phosphoprotein; Polymorphism; Pyrimidine biosynthesis; Reference proteome
1 Q14203 DCTN1 Dynactin subunit 1 1278 3D-structure; Alternative splicing; Amyotrophic lateral sclerosis; Cell cycle; Cell division; Coiled coil; Cytoplasm; Cytoskeleton; Dynein; Microtubule; Mitosis; Neurodegeneration; Neuropathy; Nucleus; Parkinsonism; Phosphoprotein; Polymorphism; Reference proteome; Transport; Ubl conjugation
2 Q92499 DDX1 ATP-dependent RNA helicase DDX1 740 3D-structure; ATP-binding; Acetylation; Activator; Alternative splicing; Antiviral defense; Cytoplasm; DNA-binding; Exonuclease; Helicase; Host-virus interaction; Hydrolase; Immunity; Innate immunity; Isopeptide bond; Mitochondrion; Nuclease; Nucleotide-binding; Nucleus; Phosphoprotein; RNA-binding; Reference proteome; Transcription; Transcription regulation; Ubl conjugation; mRNA processing; tRNA processing
2 Q9UHI6 DDX20 Probable ATP-dependent RNA helicase DDX20 824 3D-structure; ATP-binding; Alternative splicing; Cytoplasm; DNA-binding; Helicase; Hydrolase; Nucleotide-binding; Nucleus; Phosphoprotein; Polymorphism; Reference proteome; mRNA processing; mRNA splicing
2 Q9GZR7 DDX24 ATP-dependent RNA helicase DDX24 859 ATP-binding; Acetylation; Alternative splicing; Helicase; Hydrolase; Isopeptide bond; Nucleotide-binding; Phosphoprotein; Polymorphism; RNA-binding; Reference proteome; Ubl conjugation
1 O00571 DDX3X ATP-dependent RNA helicase DDX3X 662 3D-structure; ATP-binding; Acetylation; Alternative splicing; Apoptosis; Cell membrane; Cell projection; Chromosome partition; Cytoplasm; Cytoskeleton; DNA-binding; Direct protein sequencing; Disease mutation; Helicase; Host-virus interaction; Hydrolase; Immunity; Inflammasome; Innate immunity; Isopeptide bond; Membrane; Mental retardation; Methylation; Nucleotide-binding; Nucleus; Phosphoprotein; Polymorphism; RNA-binding; Reference proteome; Ribosome biogenesis; Transcription; Transcription regulation; Translation regulation; Ubl conjugation
2 Q9Y2R4 DDX52 Probable ATP-dependent RNA helicase DDX52 599 3D-structure; ATP-binding; Acetylation; Helicase; Hydrolase; Nucleotide-binding; Nucleus; Phosphoprotein; Polymorphism; RNA-binding; Reference proteome
2 O43143 DHX15 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 795 3D-structure; ATP-binding; Acetylation; Helicase; Hydrolase; Isopeptide bond; Nucleotide-binding; Nucleus; Phosphoprotein; Reference proteome; Ubl conjugation; mRNA processing; mRNA splicing
1 Q8IY37 DHX37 Probable ATP-dependent RNA helicase DHX37 1157 ATP-binding; Helicase; Hydrolase; Nucleotide-binding; Polymorphism; Reference proteome
1 Q9NSV4 DIAPH3 Protein diaphanous homolog 3 1193 3D-structure; Alternative splicing; Coiled coil; Cytoplasm; Deafness; Neuropathy; Non-syndromic deafness; Nucleus; Phosphoprotein; Polymorphism; Reference proteome; Repeat; Ubl conjugation
2 Q9UNQ2 DIMT1 Probable dimethyladenosine transferase 313 3D-structure; Methyltransferase; Nucleus; RNA-binding; Reference proteome; S-adenosyl-L-methionine; Transferase; rRNA processing
1 Q86Y56 DNAAF5 Dynein assembly factor 5, axonemal 855 Acetylation; Alternative splicing; Ciliopathy; Cilium biogenesis/degradation; Cytoplasm; Direct protein sequencing; Disease mutation; Kartagener syndrome; Polymorphism; Primary ciliary dyskinesia; Reference proteome; Repeat
2 O60884 DNAJA2 DnaJ homolog subfamily A member 2 412 Acetylation; Chaperone; Isopeptide bond; Lipoprotein; Membrane; Metal-binding; Methylation; Phosphoprotein; Prenylation; Reference proteome; Repeat; Ubl conjugation; Zinc; Zinc-finger
2 Q96EY1 DNAJA3 DnaJ homolog subfamily A member 3, mitochondrial 480 3D-structure; Acetylation; Alternative splicing; Apoptosis; Cell junction; Cell membrane; Chaperone; Cytoplasm; Membrane; Metal-binding; Methylation; Mitochondrion; Phosphoprotein; Polymorphism; Postsynaptic cell membrane; Reference proteome; Repeat; Synapse; Transit peptide; Zinc; Zinc-finger
2 O75190 DNAJB6 DnaJ homolog subfamily B member 6 326 3D-structure; Alternative splicing; Chaperone; Cytoplasm; Direct protein sequencing; Disease mutation; Limb-girdle muscular dystrophy; Methylation; Nucleus; Phosphoprotein; Reference proteome
1 P50570 DNM2 Dynamin-2 870 3D-structure; Acetylation; Alternative splicing; Cell junction; Cell projection; Charcot-Marie-Tooth disease; Coated pit; Cytoplasm; Cytoplasmic vesicle; Cytoskeleton; Disease mutation; Endocytosis; GTP-binding; Hydrolase; Membrane; Microtubule; Motor protein; Neurodegeneration; Neuropathy; Nucleotide-binding; Phagocytosis; Phosphoprotein; Polymorphism; Reference proteome; Synapse
1 Q9Y6K1 DNMT3A DNA 912 3D-structure; Alternative promoter usage; Alternative splicing; Chromatin regulator; Cytoplasm; DNA-binding; Disease mutation; Dwarfism; Isopeptide bond; Mental retardation; Metal-binding; Methylation; Methyltransferase; Nucleus; Phosphoprotein; Polymorphism; Reference proteome; Repressor; S-adenosyl-L-methionine; Transferase; Ubl conjugation; Zinc; Zinc-finger
3 O60762 DPM1 Dolichol-phosphate mannosyltransferase subunit 1 260 Acetylation; Congenital disorder of glycosylation; Congenital muscular dystrophy; Disease mutation; Dystroglycanopathy; Endoplasmic reticulum; Glycosyltransferase; Phosphoprotein; Reference proteome; Transferase
1 P15924 DSP Desmoplakin 2871 3D-structure; Alternative splicing; Cardiomyopathy; Cell junction; Cell membrane; Coiled coil; Cytoplasm; Cytoskeleton; Disease mutation; Epidermolysis bullosa; Membrane; Methylation; Palmoplantar keratoderma; Phosphoprotein; Polymorphism; Reference proteome; Repeat; SH3 domain
2 Q14204 DYNC1H1 Cytoplasmic dynein 1 heavy chain 1 4646 3D-structure; ATP-binding; Acetylation; Cell cycle; Cell division; Charcot-Marie-Tooth disease; Coiled coil; Cytoplasm; Cytoskeleton; Disease mutation; Dynein; Mental retardation; Microtubule; Mitosis; Motor protein; Neurodegeneration; Neuropathy; Nucleotide-binding; Phosphoprotein; Polymorphism; Reference proteome; Repeat; Transport
1 Q9H8V3 ECT2 Protein ECT2 914 3D-structure; Acetylation; Alternative splicing; Cell cycle; Cell division; Cell junction; Cytoplasm; Cytoskeleton; Differentiation; Guanine-nucleotide releasing factor; Isopeptide bond; Neurogenesis; Nucleus; Oncogene; Phosphoprotein; Polymorphism; Protein transport; Reference proteome; Repeat; Tight junction; Transport; Ubl conjugation
1 Q8N6R0 EEF1AKNMT eEF1A lysine and N-terminal methyltransferase 699 3D-structure; Acetylation; Alternative splicing; Methyltransferase; Multifunctional enzyme; Phosphoprotein; Polymorphism; Reference proteome; Transferase
3 P26641 EEF1G Elongation factor 1-gamma 437 3D-structure; Acetylation; Alternative splicing; Direct protein sequencing; Elongation factor; Isopeptide bond; Protein biosynthesis; Reference proteome; Ubl conjugation
4 Q15029 EFTUD2 116 kDa U5 small nuclear ribonucleoprotein component 972 3D-structure; Acetylation; Alternative splicing; Disease mutation; GTP-binding; Isopeptide bond; Mental retardation; Nucleotide-binding; Nucleus; Phosphoprotein; Polymorphism; Reference proteome; Spliceosome; Ubl conjugation; mRNA processing; mRNA splicing
2 Q13347 EIF3I Eukaryotic translation initiation factor 3 subunit I 325 Acetylation; Cytoplasm; Direct protein sequencing; Initiation factor; Isopeptide bond; Phosphoprotein; Protein biosynthesis; Reference proteome; Repeat; Ubl conjugation; WD repeat
2 P60842 EIF4A1 Eukaryotic initiation factor 4A-I 406 3D-structure; ATP-binding; Acetylation; Alternative splicing; Helicase; Host-virus interaction; Hydrolase; Initiation factor; Isopeptide bond; Nucleotide-binding; Phosphoprotein; Protein biosynthesis; RNA-binding; Reference proteome; Ubl conjugation
2 Q9NRA8 EIF4ENIF1 Eukaryotic translation initiation factor 4E transporter 985 3D-structure; Acetylation; Alternative splicing; Cytoplasm; Isopeptide bond; Nucleus; Phosphoprotein; Protein transport; Reference proteome; Transport; Ubl conjugation
1 P78545 ELF3 ETS-related transcription factor Elf-3 371 3D-structure; Activator; Alternative splicing; Cytoplasm; DNA-binding; Developmental protein; Differentiation; Inflammatory response; Nucleus; Polymorphism; Reference proteome; Repressor; Transcription; Transcription regulation
3 O95163 ELP1 Elongator complex protein 1 1332 3D-structure; Cytoplasm; Direct protein sequencing; Disease mutation; Neurodegeneration; Neuropathy; Nucleus; Phosphoprotein; Reference proteome; Transcription; Transcription regulation; tRNA processing
2 Q09472 EP300 Histone acetyltransferase p300 2414 3D-structure; Acetylation; Acyltransferase; Biological rhythms; Bromodomain; Cell cycle; Chromosomal rearrangement; Chromosome; Citrullination; Cytoplasm; Direct protein sequencing; Disease mutation; Host-virus interaction; Isopeptide bond; Mental retardation; Metal-binding; Methylation; Nucleus; Phosphoprotein; Polymorphism; Reference proteome; Repeat; Transcription; Transcription regulation; Transferase; Ubl conjugation; Zinc; Zinc-finger
4 Q96L91 EP400 E1A-binding protein p400 3159 ATP-binding; Acetylation; Alternative splicing; Chromatin regulator; DNA-binding; Helicase; Hydrolase; Nucleotide-binding; Nucleus; Phosphoprotein; Polymorphism; Reference proteome
1 P58107 EPPK1 Epiplakin 5088 Cell junction; Cell membrane; Cell projection; Coiled coil; Cytoplasm; Cytoskeleton; Direct protein sequencing; Disease mutation; Membrane; Phosphoprotein; Reference proteome; Repeat; Tight junction
2 P19447 ERCC3 General transcription and DNA repair factor IIH helicase subunit XPB 782 3D-structure; ATP-binding; Cockayne syndrome; DNA damage; DNA repair; DNA-binding; Deafness; Disease mutation; Dwarfism; Helicase; Host-virus interaction; Hydrolase; Ichthyosis; Nucleotide-binding; Nucleus; Phosphoprotein; Polymorphism; Reference proteome; Transcription; Transcription regulation; Xeroderma pigmentosum
2 P13804 ETFA Electron transfer flavoprotein subunit alpha, mitochondrial 333 3D-structure; Acetylation; Alternative splicing; Direct protein sequencing; Disease mutation; Electron transport; FAD; Flavoprotein; Glutaricaciduria; Mitochondrion; Phosphoprotein; Polymorphism; Reference proteome; Transit peptide; Transport
2 Q9NV70 EXOC1 Exocyst complex component 1 894 Alternative splicing; Antiviral defense; Coiled coil; Cytoplasm; Direct protein sequencing; Exocytosis; Host-virus interaction; Phosphoprotein; Protein transport; Reference proteome; Transport
1 O60645 EXOC3 Exocyst complex component 3 745 Acetylation; Cell projection; Cytoplasm; Exocytosis; Golgi apparatus; Protein transport; Reference proteome; Transport
1 Q96A65 EXOC4 Exocyst complex component 4 974 Acetylation; Alternative splicing; Cell projection; Coiled coil; Direct protein sequencing; Exocytosis; Phosphoprotein; Polymorphism; Protein transport; Reference proteome; Transport
User defined P63073 Eif4e Eukaryotic translation initiation factor 4E 217 3D-structure; Acetylation; Cytoplasm; Initiation factor; Phosphoprotein; Protein biosynthesis; RNA-binding; Reference proteome; Translation regulation
2 Q9BXW9 FANCD2 Fanconi anemia group D2 protein 1451 3D-structure; Alternative splicing; Cell cycle; DNA damage; DNA repair; Disease mutation; Fanconi anemia; Isopeptide bond; Nucleus; Phosphoprotein; Polymorphism; Reference proteome; Ubl conjugation
1 Q9NVI1 FANCI Fanconi anemia group I protein 1328 3D-structure; Alternative splicing; Cell cycle; Cytoplasm; Direct protein sequencing; Disease variant; DNA damage; DNA repair; DNA-binding; Fanconi anemia; Isopeptide bond; Nucleus; Phosphoprotein; Reference proteome; Ubl conjugation;
1 Q9NYY8 FASTKD2 FAST kinase domain-containing protein 2, mitochondrial 710 Alternative splicing; Mitochondrion; Mitochondrion nucleoid; Phosphoprotein; Polymorphism; RNA-binding; Reference proteome; Ribosome biogenesis; Transit peptide; rRNA-binding
2 P22087 FBL rRNA 2'-O-methyltransferase fibrillarin 321 3D-structure; Acetylation; Isopeptide bond; Methylation; Methyltransferase; Nucleus; Phosphoprotein; RNA-binding; Reference proteome; Ribonucleoprotein; S-adenosyl-L-methionine; Transferase; Ubl conjugation; rRNA processing
4 Q969H0 FBXW7 F-box/WD repeat-containing protein 7 707 3D-structure; Alternative splicing; Biological rhythms; Cytoplasm; Host-virus interaction; Nucleus; Phosphoprotein; Polymorphism; Reference proteome; Repeat; Ubl conjugation; Ubl conjugation pathway; WD repeat
2 Q8N3Y1 FBXW8 F-box/WD repeat-containing protein 8 598 Acetylation; Alternative splicing; Cytoplasm; Golgi apparatus; Phosphoprotein; Polymorphism; Reference proteome; Repeat; Ubl conjugation pathway; WD repeat
3 Q14697 GANAB Neutral alpha-glucosidase AB 944 Alternative splicing; Direct protein sequencing; Disease mutation; Disulfide bond; Endoplasmic reticulum; Glycoprotein; Glycosidase; Golgi apparatus; Hydrolase; Phosphoprotein; Polymorphism; Reference proteome; Signal
2 Q92947 GCDH Glutaryl-CoA dehydrogenase, mitochondrial 438 3D-structure; Acetylation; Alternative splicing; Disease mutation; FAD; Flavoprotein; Glutaricaciduria; Mitochondrion; Oxidoreductase; Polymorphism; Reference proteome; Transit peptide
2 Q92616 GCN1 eIF-2-alpha kinase activator GCN1 2671 Acetylation; Activator; Coiled coil; Cytoplasm; Direct protein sequencing; Phosphoprotein; Polymorphism; Reference proteome; Repeat; Stress response; Translation regulation
1 P57678 GEMIN4 Gem-associated protein 4 1058 Acetylation; Cytoplasm; Disease mutation; Nucleus; Phosphoprotein; Polymorphism; Reference proteome; mRNA processing; mRNA splicing
1 Q9BVP2 GNL3 Guanine nucleotide-binding protein-like 3 549 Acetylation; Alternative splicing; Coiled coil; GTP-binding; Isopeptide bond; Nucleotide-binding; Nucleus; Phosphoprotein; Polymorphism; Reference proteome; Ubl conjugation
3 P49841 GSK3B Glycogen synthase kinase-3 beta 420 3D-structure; ADP-ribosylation; ATP-binding; Alternative splicing; Alzheimer disease; Biological rhythms; Carbohydrate metabolism; Cell membrane; Cytoplasm; Developmental protein; Diabetes mellitus; Differentiation; Glycogen metabolism; Kinase; Membrane; Neurogenesis; Nucleotide-binding; Nucleus; Phosphoprotein; Reference proteome; Serine/threonine-protein kinase; Signal transduction inhibitor; Transferase; Wnt signaling pathway
User defined Q00403 GTF2B Transcription initiation factor IIB 316 3D-structure; Acetylation; Acyltransferase; Chromosome; DNA-binding; Host-virus interaction; Metal-binding; Nucleus; Phosphoprotein; Polymorphism; Reference proteome; Repeat; Transcription; Transcription regulation; Transferase; Zinc; Zinc-finger
1 P35269 GTF2F1 General transcription factor IIF subunit 1 517 3D-structure; Acetylation; DNA-binding; Direct protein sequencing; Nucleus; Phosphoprotein; Polymorphism; Reference proteome; Transcription; Transcription regulation
2 P78347 GTF2I General transcription factor II-I 998 3D-structure; Acetylation; Alternative splicing; Cytoplasm; DNA-binding; Direct protein sequencing; Isopeptide bond; Nucleus; Phosphoprotein; Polymorphism; Reference proteome; Repeat; Transcription; Transcription regulation; Ubl conjugation; Williams-Beuren syndrome
2 Q12789 GTF3C1 General transcription factor 3C polypeptide 1 2109 Alternative splicing; DNA-binding; Direct protein sequencing; Isopeptide bond; Nucleus; Phosphoprotein; Polymorphism; Reference proteome; Transcription; Ubl conjugation
2 Q8WUA4 GTF3C2 General transcription factor 3C polypeptide 2 911 Alternative splicing; Direct protein sequencing; Nucleus; Phosphoprotein; Reference proteome; Repeat; Transcription; WD repeat
3 Q9Y5Q9 GTF3C3 General transcription factor 3C polypeptide 3 886 Acetylation; Alternative splicing; DNA-binding; Nucleus; Phosphoprotein; Polymorphism; Reference proteome; Repeat; TPR repeat; Transcription
3 Q9UKN8 GTF3C4 General transcription factor 3C polypeptide 4 822 Acetylation; Acyltransferase; DNA-binding; Direct protein sequencing; Isopeptide bond; Nucleus; Phosphoprotein; Reference proteome; Transcription; Transferase; Ubl conjugation
2 Q99880 H2BC13 Histone H2B type 1-L 126 ADP-ribosylation; Acetylation; Chromosome; DNA-binding; Direct protein sequencing; Glycoprotein; Hydroxylation; Isopeptide bond; Methylation; Nucleosome core; Nucleus; Phosphoprotein; Polymorphism; Reference proteome; Ubl conjugation
4 P55084 HADHB Trifunctional enzyme subunit beta, mitochondrial 474 3D-structure; Acetylation; Acyltransferase; Alternative splicing; Direct protein sequencing; Disease mutation; Endoplasmic reticulum; Fatty acid metabolism; Lipid metabolism; Membrane; Mitochondrion; Mitochondrion inner membrane; Mitochondrion outer membrane; Polymorphism; Reference proteome; Transferase; Transit peptide
2 Q8TF76 HASPIN Serine/threonine-protein kinase haspin 798 3D-structure; ATP-binding; Alternative splicing; Cell cycle; Chromatin regulator; Chromosome; Cytoplasm; Cytoskeleton; Kinase; Magnesium; Nucleotide-binding; Nucleus; Phosphoprotein; Polymorphism; Reference proteome; Serine/threonine-protein kinase; Transferase
5 Q13547 HDAC1 Histone deacetylase 1 482 3D-structure; Acetylation; Biological rhythms; Chromatin regulator; Hydrolase; Isopeptide bond; Methylation; Nucleus; Phosphoprotein; Reference proteome; Repressor; S-nitrosylation; Transcription; Transcription regulation; Ubl conjugation;
2 Q92769 HDAC2 Histone deacetylase 2 488 3D-structure; Acetylation; Alternative splicing; Biological rhythms; Chromatin regulator; Cytoplasm; Hydrolase; Isopeptide bond; Nucleus; Phosphoprotein; Polymorphism; Reference proteome; Repressor; S-nitrosylation; Transcription; Transcription regulation; Ubl conjugation
1 Q9H583 HEATR1 HEAT repeat-containing protein 1 2144 Acetylation; Nucleus; Phosphoprotein; Polymorphism; Reference proteome; Ribonucleoprotein; Ribosome biogenesis; Transcription; Transcription regulation; rRNA processing
1 Q7Z4Q2 HEATR3 HEAT repeat-containing protein 3 680 Alternative splicing; Phosphoprotein; Polymorphism; Reference proteome; Repeat
2 Q9NRZ9 HELLS Lymphoid-specific helicase 838 ATP-binding; Alternative splicing; Cell cycle; Cell division; Coiled coil; Developmental protein; Disease mutation; Helicase; Hydrolase; Mitosis; Nucleotide-binding; Nucleus; Phosphoprotein; Polymorphism; Reference proteome; Transcription; Transcription regulation
2 Q9Y241 HIGD1A HIG1 domain family member 1A, mitochondrial 93 3D-structure; Acetylation; Alternative splicing; Direct protein sequencing; Electron transport; Membrane; Mitochondrion; Mitochondrion inner membrane; Phosphoprotein; Reference proteome; Respiratory chain; Stress response; Transmembrane; Transmembrane helix; Transport
2 Q13151 HNRNPA0 Heterogeneous nuclear ribonucleoprotein A0 305 Acetylation; Direct protein sequencing; Isopeptide bond; Methylation; Nucleus; Phosphoprotein; RNA-binding; Reference proteome; Repeat; Ribonucleoprotein; Ubl conjugation
2 P07910 HNRNPC Heterogeneous nuclear ribonucleoproteins C1/C2 306 3D-structure; Acetylation; Alternative splicing; Coiled coil; Direct protein sequencing; Isopeptide bond; Nucleus; Phosphoprotein; RNA-binding; Reference proteome; Ribonucleoprotein; Spliceosome; Ubl conjugation; mRNA processing; mRNA splicing
2 P52597 HNRNPF Heterogeneous nuclear ribonucleoprotein F 415 3D-structure; Acetylation; Direct protein sequencing; Isopeptide bond; Nucleus; Phosphoprotein; Polymorphism; RNA-binding; Reference proteome; Repeat; Ribonucleoprotein; Spliceosome; Ubl conjugation; mRNA processing; mRNA splicing
2 P61978 HNRNPK Heterogeneous nuclear ribonucleoprotein K 463 3D-structure; Acetylation; Activator; Alternative splicing; Cell junction; Cell projection; Cytoplasm; DNA-binding; Direct protein sequencing; Glycoprotein; Host-virus interaction; Isopeptide bond; Mental retardation; Methylation; Nucleus; Phosphoprotein; RNA-binding; Reference proteome; Repeat; Repressor; Ribonucleoprotein; Spliceosome; Transcription; Transcription regulation; Ubl conjugation; mRNA processing; mRNA splicing
1 P07900 HSP90AA1 Heat shock protein HSP 90-alpha 732 3D-structure; ATP-binding; Acetylation; Alternative splicing; Cell membrane; Chaperone; Cytoplasm; Direct protein sequencing; Host-virus interaction; Membrane; Nucleotide-binding; Nucleus; Phosphoprotein; Reference proteome; S-nitrosylation; Stress response; Ubl conjugation
4 P04792 HSPB1 Heat shock protein beta-1 205 3D-structure; Acetylation; Chaperone; Charcot-Marie-Tooth disease; Cytoplasm; Cytoskeleton; Direct protein sequencing; Disease variant; Host-virus interaction; Methylation; Neurodegeneration; Neuropathy; Nucleus; Phosphoprotein; Reference proteome; Stress response;
2 P10809 HSPD1 60 kDa heat shock protein, mitochondrial 573 3D-structure; ATP-binding; Acetylation; Alternative splicing; Chaperone; Direct protein sequencing; Disease mutation; Hereditary spastic paraplegia; Host-virus interaction; Isomerase; Isopeptide bond; Leukodystrophy; Mitochondrion; Neurodegeneration; Nucleotide-binding; Phosphoprotein; Reference proteome; Transit peptide; Ubl conjugation
3 Q92598 HSPH1 Heat shock protein 105 kDa 858 3D-structure; ATP-binding; Acetylation; Alternative splicing; Cytoplasm; Direct protein sequencing; Nucleotide-binding; Phosphoprotein; Reference proteome; Stress response
2 Q7Z6Z7 HUWE1 E3 ubiquitin-protein ligase HUWE1 4374 3D-structure; Acetylation; Alternative splicing; Biological rhythms; Chromosomal rearrangement; Cytoplasm; DNA damage; DNA repair; DNA-binding; Differentiation; Disease mutation; Mental retardation; Methylation; Nucleus; Phosphoprotein; Polymorphism; Reference proteome; Transferase; Ubl conjugation pathway
2 P50213 IDH3A Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial 366 3D-structure; Acetylation; Alternative splicing; Direct protein sequencing; Magnesium; Manganese; Metal-binding; Mitochondrion; NAD; Oxidoreductase; Phosphoprotein; Reference proteome; Transit peptide; Tricarboxylic acid cycle
2 O43837 IDH3B Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial 385 3D-structure; Acetylation; Alternative splicing; Disease mutation; Mitochondrion; Polymorphism; Reference proteome; Retinitis pigmentosa; Transit peptide; Tricarboxylic acid cycle
2 P51553 IDH3G Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial 393 3D-structure; ATP-binding; Alternative splicing; Magnesium; Manganese; Metal-binding; Mitochondrion; Nucleotide-binding; Reference proteome; Transit peptide; Tricarboxylic acid cycle
2 Q9NZI8 IGF2BP1 Insulin-like growth factor 2 mRNA-binding protein 1 577 3D-structure; Alternative splicing; Cell junction; Cell projection; Cytoplasm; Direct protein sequencing; Nucleus; Phosphoprotein; RNA-binding; Reference proteome; Repeat; Synapse; Translation regulation; Transport; mRNA transport
1 Q9UI26 IPO11 Importin-11 975 Acetylation; Alternative splicing; Cytoplasm; Nucleus; Phosphoprotein; Polymorphism; Protein transport; Reference proteome; Repeat; Transport
2 O94829 IPO13 Importin-13 963 3D-structure; Cytoplasm; Nucleus; Protein transport; Reference proteome; Repeat; Transport
2 Q8TEX9 IPO4 Importin-4 1081 3D-structure; Acetylation; Alternative splicing; Cytoplasm; Direct protein sequencing; Nucleus; Polymorphism; Protein transport; Reference proteome; Repeat; Transport
2 O95373 IPO7 Importin-7 1038 Acetylation; Cytoplasm; Direct protein sequencing; Host-virus interaction; Nucleus; Phosphoprotein; Polymorphism; Protein transport; Reference proteome; Transport
2 Q96P70 IPO9 Importin-9 1041 3D-structure; Acetylation; Cytoplasm; Direct protein sequencing; Nucleus; Protein transport; Reference proteome; Transport
1 P46940 IQGAP1 Ras GTPase-activating-like protein IQGAP1 1657 3D-structure; Acetylation; Calmodulin-binding; Cell membrane; Cytoplasm; Direct protein sequencing; Host-virus interaction; Membrane; Nucleus; Phosphoprotein; Polymorphism; Reference proteome; Repeat
2 Q13576 IQGAP2 Ras GTPase-activating-like protein IQGAP2 1575 3D-structure; Alternative splicing; Calmodulin-binding; Direct protein sequencing; Phosphoprotein; Polymorphism; Reference proteome; Repeat
2 Q86VI3 IQGAP3 Ras GTPase-activating-like protein IQGAP3 1631 3D-structure; Calmodulin-binding; Phosphoprotein; Polymorphism; Reference proteome; Repeat
2 P51617 IRAK1 Interleukin-1 receptor-associated kinase 1 712 3D-structure; ATP-binding; Alternative splicing; Cytoplasm; Direct protein sequencing; Host-virus interaction; Immunity; Innate immunity; Isopeptide bond; Kinase; Lipid droplet; Magnesium; Nucleotide-binding; Nucleus; Phosphoprotein; Polymorphism; Reference proteome; Serine/threonine-protein kinase; Transferase; Ubl conjugation
2 O14654 IRS4 Insulin receptor substrate 4 1257 Cell membrane; Congenital hypothyroidism; Direct protein sequencing; Disease mutation; Membrane; Phosphoprotein; Polymorphism; Reference proteome; Repeat; Transducer
1 Q92830 KAT2A Histone acetyltransferase KAT2A 837 3D-structure; Acetylation; Acyltransferase; Alternative splicing; Bromodomain; Chromosome; Cytoplasm; Cytoskeleton; Host-virus interaction; Isopeptide bond; Nucleus; Reference proteome; Transcription; Transcription regulation; Transferase; Ubl conjugation
1 Q92831 KAT2B Histone acetyltransferase KAT2B 832 3D-structure; Activator; Acyltransferase; Biological rhythms; Bromodomain; Cell cycle; Cytoplasm; Cytoskeleton; Disease mutation; Host-virus interaction; Nucleus; Polymorphism; Reference proteome; Transcription; Transcription regulation; Transferase
1 Q92993 KAT5 Histone acetyltransferase KAT5 513 3D-structure; Acetylation; Activator; Acyltransferase; Alternative splicing; Chromatin regulator; Cytoplasm; Direct protein sequencing; Growth regulation; Host-virus interaction; Isopeptide bond; Metal-binding; Nucleus; Phosphoprotein; Polymorphism; Reference proteome; Transcription; Transcription regulation; Transferase; Ubl conjugation; Zinc; Zinc-finger
2 P52292 KPNA2 Importin subunit alpha-1 529 3D-structure; Acetylation; Cytoplasm; Direct protein sequencing; Host-virus interaction; Nucleus; Phosphoprotein; Polymorphism; Protein transport; Reference proteome; Repeat; Transport
2 O00629 KPNA4 Importin subunit alpha-3 521 3D-structure; Acetylation; Cytoplasm; Host-virus interaction; Nucleus; Phosphoprotein; Protein transport; Reference proteome; Repeat; Transport
2 Q14974 KPNB1 Importin subunit beta-1 876 3D-structure; ADP-ribosylation; Acetylation; Alternative splicing; Cytoplasm; Direct protein sequencing; Host-virus interaction; Nucleus; Phosphoprotein; Protein transport; Reference proteome; Repeat; Transport
1 Q9Y4W2 LAS1L Ribosomal biogenesis protein LAS1L 734 Alternative splicing; Cytoplasm; Disease mutation; Isopeptide bond; Mental retardation; Nucleus; Obesity; Phosphoprotein; Polymorphism; Reference proteome; Ubl conjugation; rRNA processing
1 Q14739 LBR Delta 615 3D-structure; Acetylation; Cholesterol biosynthesis; Cholesterol metabolism; Cytoplasm; DNA-binding; Disease mutation; Dwarfism; Endoplasmic reticulum; Lipid biosynthesis; Lipid metabolism; Membrane; Nucleus; Oxidoreductase; Phosphoprotein; Polymorphism; Receptor; Reference proteome; Steroid biosynthesis; Steroid metabolism; Sterol biosynthesis; Sterol metabolism; Transmembrane; Transmembrane helix
4 P02545 LMNA Prelamin-A/C [Cleaved into: Lamin-A/C 664 3D-structure; Acetylation; Alternative splicing; Cardiomyopathy; Charcot-Marie-Tooth disease; Coiled coil; Congenital muscular dystrophy; Direct protein sequencing; Disease mutation; Emery-Dreifuss muscular dystrophy; Intermediate filament; Isopeptide bond; Limb-girdle muscular dystrophy; Lipoprotein; Methylation; Neurodegeneration; Neuropathy; Nucleus; Phosphoprotein; Polymorphism; Prenylation; Reference proteome; Ubl conjugation
2 P36776 LONP1 Lon protease homolog, mitochondrial 959 3D-structure; ATP-binding; Alternative splicing; Cataract; DNA-binding; Deafness; Disease mutation; Dwarfism; Hydrolase; Mitochondrion; Nucleotide-binding; Polymorphism; Protease; Reference proteome; Serine protease; Transit peptide
3 P42704 LRPPRC Leucine-rich PPR motif-containing protein, mitochondrial 1394 Acetylation; DNA-binding; Direct protein sequencing; Disease mutation; Leigh syndrome; Membrane; Mitochondrion; Nucleus; Phosphoprotein; Polymorphism; Primary mitochondrial disease; RNA-binding; Reference proteome; Repeat; Transcription; Transcription regulation; Transit peptide; Transport; mRNA transport
1 Q9UNF1 MAGED2 Melanoma-associated antigen D2 606 Acetylation; Alternative splicing; Bartter syndrome; Direct protein sequencing; Disease mutation; Phosphoprotein; Polymorphism; Reference proteome; Tumor antigen
2 Q02750 MAP2K1 Dual specificity mitogen-activated protein kinase kinase 1 393 3D-structure; ATP-binding; Acetylation; Alternative splicing; Cardiomyopathy; Cytoplasm; Cytoskeleton; Direct protein sequencing; Disease mutation; Ectodermal dysplasia; Kinase; Membrane; Mental retardation; Nucleotide-binding; Nucleus; Phosphoprotein; Reference proteome; Serine/threonine-protein kinase; Transferase; Tyrosine-protein kinase
1 P28482 MAPK1 Mitogen-activated protein kinase 1 360 3D-structure; Acetylation; Alternative splicing; Apoptosis; ATP-binding; Cell cycle; Cell junction; Cytoplasm; Cytoskeleton; Direct protein sequencing; Disease variant; DNA-binding; Host-virus interaction; Kinase; Membrane; Nucleotide-binding; Nucleus; Phosphoprotein; Reference proteome; Repressor; Serine/threonine-protein kinase; Transcription; Transcription regulation; Transferase; Ubl conjugation;
1 P27361 MAPK3 Mitogen-activated protein kinase 3 379 3D-structure; ATP-binding; Acetylation; Alternative splicing; Apoptosis; Cell cycle; Cytoplasm; Direct protein sequencing; Host-virus interaction; Kinase; Membrane; Nucleotide-binding; Nucleus; Phosphoprotein; Polymorphism; Reference proteome; Serine/threonine-protein kinase; Transferase
1 Q13164 MAPK7 Mitogen-activated protein kinase 7 816 3D-structure; ATP-binding; Acetylation; Alternative splicing; Cell cycle; Cytoplasm; Differentiation; Direct protein sequencing; Kinase; Nucleotide-binding; Nucleus; Phosphoprotein; Polymorphism; Reference proteome; Serine/threonine-protein kinase; Transferase
1 P45983 MAPK8 Mitogen-activated protein kinase 8 427 3D-structure; ATP-binding; Alternative splicing; Biological rhythms; Cell junction; Cytoplasm; Kinase; Nucleotide-binding; Nucleus; Phosphoprotein; Polymorphism; Reference proteome; S-nitrosylation; Serine/threonine-protein kinase; Synapse; Transferase
2 P56192 MARS1 Methionine--tRNA ligase, cytoplasmic 900 3D-structure; ATP-binding; Alternative splicing; Aminoacyl-tRNA synthetase; Charcot-Marie-Tooth disease; Cytoplasm; Disease mutation; Ligase; Neurodegeneration; Neuropathy; Nucleotide-binding; Nucleus; Phosphoprotein; Polymorphism; Protein biosynthesis; RNA-binding; Reference proteome; tRNA-binding
1 P43243 MATR3 Matrin-3 847 Acetylation; Alternative splicing; Amyotrophic lateral sclerosis; Direct protein sequencing; Disease mutation; Immunity; Innate immunity; Isopeptide bond; Metal-binding; Neurodegeneration; Nucleus; Phosphoprotein; Polymorphism; RNA-binding; Reference proteome; Repeat; Ubl conjugation; Zinc; Zinc-finger
14 P61244 MAX Protein max 160 3D-structure; Acetylation; Activator; Alternative splicing; Cell projection; DNA-binding; Disease mutation; Nucleus; Phosphoprotein; Polymorphism; Reference proteome; Repressor; Transcription; Transcription regulation
2 P25205 MCM3 DNA replication licensing factor MCM3 808 ATP-binding; Acetylation; Alternative splicing; Cell cycle; DNA replication; DNA-binding; Direct protein sequencing; Glycoprotein; Helicase; Hydrolase; Nucleotide-binding; Nucleus; Phosphoprotein; Polymorphism; Reference proteome
6 P33993 MCM7 DNA replication licensing factor MCM7 719 ATP-binding; Acetylation; Alternative splicing; Cell cycle; DNA replication; DNA-binding; Direct protein sequencing; Glycoprotein; Helicase; Hydrolase; Isopeptide bond; Nucleotide-binding; Nucleus; Phosphoprotein; Polymorphism; Reference proteome; Ubl conjugation
1 Q9NU22 MDN1 Midasin 5596 ATP-binding; Acetylation; Chaperone; Cytoplasm; Nucleotide-binding; Nucleus; Phosphoprotein; Polymorphism; Reference proteome; Repeat
1 Q93074 MED12 Mediator of RNA polymerase II transcription subunit 12 2177 Acetylation; Activator; Alternative splicing; Direct protein sequencing; Disease mutation; Mental retardation; Methylation; Nucleus; Phosphoprotein; Reference proteome; Repressor; Transcription; Transcription regulation
User defined O60244 MED14 Mediator of RNA polymerase II transcription subunit 14 1454 Activator; Direct protein sequencing; Nucleus; Phosphoprotein; Polymorphism; Reference proteome; Repeat; Transcription; Transcription regulation
1 Q9UL63 MKLN1 Muskelin 735 Acetylation; Alternative splicing; Cell junction; Cell projection; Cytoplasm; Kelch repeat; Nucleus; Polymorphism; Reference proteome; Repeat; Synapse
1 P40692 MLH1 DNA mismatch repair protein Mlh1 756 3D-structure; ATP-binding; Acetylation; Alternative splicing; Cell cycle; Chromosome; DNA damage; DNA repair; Disease mutation; Hereditary nonpolyposis colorectal cancer; Nucleotide-binding; Nucleus; Phosphoprotein; Polymorphism; Reference proteome; Tumor suppressor
2 Q96T76 MMS19 MMS19 nucleotide excision repair protein homolog 1030 Acetylation; Activator; Alternative splicing; Chromosome partition; Cytoplasm; Cytoskeleton; DNA damage; DNA repair; Nucleus; Phosphoprotein; Polymorphism; Reference proteome; Repeat; Transcription; Transcription regulation; Ubl conjugation
2 Q13724 MOGS Mannosyl-oligosaccharide glucosidase 837 Alternative splicing; Disease mutation; Endoplasmic reticulum; Glycoprotein; Glycosidase; Hydrolase; Membrane; Polymorphism; Reference proteome; Signal-anchor; Transmembrane; Transmembrane helix
1 Q9UQ07 MOK MAPK/MAK/MRK overlapping kinase 419 ATP-binding; Alternative splicing; Cell projection; Cytoplasm; Kinase; Magnesium; Metal-binding; Nucleotide-binding; Nucleus; Phosphoprotein; Polymorphism; Reference proteome; Serine/threonine-protein kinase; Transferase
2 P82650 MRPS22 28S ribosomal protein S22, mitochondrial 360 3D-structure; Acetylation; Alternative splicing; Disease mutation; Mitochondrion; Phosphoprotein; Primary mitochondrial disease; Reference proteome; Ribonucleoprotein; Ribosomal protein
2 P82930 MRPS34 28S ribosomal protein S34, mitochondrial 218 3D-structure; Disease mutation; Mitochondrion; Polymorphism; Primary mitochondrial disease; Reference proteome; Ribonucleoprotein; Ribosomal protein
2 P43246 MSH2 DNA mismatch repair protein Msh2 934 3D-structure; ATP-binding; Acetylation; Alternative splicing; Chromosome; DNA damage; DNA repair; DNA-binding; Disease mutation; Hereditary nonpolyposis colorectal cancer; Isopeptide bond; Nucleotide-binding; Nucleus; Phosphoprotein; Polymorphism; Reference proteome; Tumor suppressor; Ubl conjugation
2 P20585 MSH3 DNA mismatch repair protein Msh3 1137 3D-structure; ATP-binding; DNA damage; DNA repair; DNA-binding; Nucleotide-binding; Phosphoprotein; Polymorphism; Reference proteome
2 P52701 MSH6 DNA mismatch repair protein Msh6 1360 3D-structure; ATP-binding; Acetylation; Alternative splicing; Chromosome; DNA damage; DNA repair; DNA-binding; Direct protein sequencing; Disease mutation; Hereditary nonpolyposis colorectal cancer; Host-virus interaction; Nucleotide-binding; Nucleus; Phosphoprotein; Polymorphism; Reference proteome
1 Q6UB35 MTHFD1L Monofunctional C1-tetrahydrofolate synthase, mitochondrial 978 ATP-binding; Acetylation; Alternative splicing; Direct protein sequencing; Ligase; Mitochondrion; Nucleotide-binding; One-carbon metabolism; Phosphoprotein; Polymorphism; Reference proteome; Transit peptide
1 Q05195 MXD1 Max dimerization protein 1 221 3D-structure; Alternative splicing; DNA-binding; Nucleus; Reference proteome; Repressor; Transcription; Transcription regulation; Ubl conjugation
1 P50539 MXI1 Max-interacting protein 1 228 Alternative splicing; DNA-binding; Disease mutation; Nucleus; Proto-oncogene; Reference proteome; Repressor; Transcription; Transcription regulation
2 Q9BQG0 MYBBP1A Myb-binding protein 1A 1328 Acetylation; Activator; Alternative splicing; Biological rhythms; Citrullination; Cytoplasm; Isopeptide bond; Nucleus; Phosphoprotein; Polymorphism; Reference proteome; Repressor; Ribosome biogenesis; Transcription; Transcription regulation; Ubl conjugation
1 Q99417 MYCBP c-Myc-binding protein 103 3D-structure; Cytoplasm; Direct protein sequencing; Mitochondrion; Nucleus; Reference proteome; Transcription; Transcription regulation
1 O75592 MYCBP2 E3 ubiquitin-protein ligase MYCBP2 4678 3D-structure; Alternative splicing; Biological rhythms; Cell projection; Cytoplasm; Cytoskeleton; Disulfide bond; Guanine-nucleotide releasing factor; Metal-binding; Nucleus; Phosphoprotein; Polymorphism; Reference proteome; Repeat; Transferase; Ubl conjugation; Ubl conjugation pathway; Zinc; Zinc-finger
1 O43795 MYO1B Unconventional myosin-Ib 1136 ATP-binding; Actin-binding; Alternative splicing; Calmodulin-binding; Isopeptide bond; Motor protein; Myosin; Nucleotide-binding; Phosphoprotein; Polymorphism; Reference proteome; Repeat; Ubl conjugation
1 Q9Y4I1 MYO5A Unconventional myosin-Va 1855 3D-structure; ATP-binding; Acetylation; Actin-binding; Alternative splicing; Calmodulin-binding; Coiled coil; Motor protein; Myosin; Nucleotide-binding; Phosphoprotein; Polymorphism; Protein transport; Reference proteome; Repeat; Transport
2 Q9NQX4 MYO5C Unconventional myosin-Vc 1742 3D-structure; ATP-binding; Acetylation; Actin-binding; Alternative splicing; Calmodulin-binding; Coiled coil; Direct protein sequencing; Motor protein; Myosin; Nucleotide-binding; Polymorphism; Reference proteome; Repeat
2 Q13459 MYO9B Unconventional myosin-IXb 2157 3D-structure; ATP-binding; Acetylation; Actin-binding; Alternative splicing; Calmodulin-binding; Coiled coil; Cytoplasm; Cytoskeleton; GTPase activation; Metal-binding; Motor protein; Myosin; Nucleotide-binding; Phosphoprotein; Reference proteome; Repeat; Zinc; Zinc-finger
1 P52164 Max Protein max 160 Acetylation; Activator; Alternative splicing; Cell projection; DNA-binding; Nucleus; Phosphoprotein; Reference proteome; Repressor; Transcription; Transcription regulation
1 P42695 NCAPD3 Condensin-2 complex subunit D3 1498 Cell cycle; Cell division; Coiled coil; Disease variant; DNA condensation; Mitosis; Nucleus; Phosphoprotein; Primary microcephaly; Reference proteome; Repeat;
1 Q86XI2 NCAPG2 Condensin-2 complex subunit G2 1143 Alternative splicing; Cell cycle; Cell division; DNA condensation; Disease mutation; Mitosis; Nucleus; Phosphoprotein; Polymorphism; Reference proteome
2 P19338 NCL Nucleolin 710 3D-structure; Acetylation; Cytoplasm; DNA-binding; Direct protein sequencing; Isopeptide bond; Methylation; Nucleus; Phosphoprotein; Polymorphism; RNA-binding; Reference proteome; Repeat; Ubl conjugation
2 Q16718 NDUFA5 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 116 3D-structure; Acetylation; Alternative splicing; Electron transport; Membrane; Mitochondrion; Mitochondrion inner membrane; Reference proteome; Respiratory chain; Transport
2 P51970 NDUFA8 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 172 3D-structure; Direct protein sequencing; Disease variant; Disulfide bond; Electron transport; Membrane; Mitochondrion; Mitochondrion inner membrane; Primary mitochondrial disease; Reference proteome; Repeat; Respiratory chain; Transport;
2 P28331 NDUFS1 NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial 727 2Fe-2S; 3D-structure; 4Fe-4S; Acetylation; Alternative splicing; Direct protein sequencing; Disease mutation; Electron transport; Iron; Iron-sulfur; Membrane; Metal-binding; Mitochondrion; Mitochondrion inner membrane; NAD; Oxidoreductase; Polymorphism; Primary mitochondrial disease; Reference proteome; Respiratory chain; Transit peptide; Translocase; Transport; Ubiquinone
3 O75306 NDUFS2 NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial 463 3D-structure; 4Fe-4S; Acetylation; Alternative splicing; Disease mutation; Electron transport; Iron; Iron-sulfur; Membrane; Metal-binding; Methylation; Mitochondrion; Mitochondrion inner membrane; NAD; Oxidoreductase; Polymorphism; Primary mitochondrial disease; Reference proteome; Respiratory chain; Transit peptide; Translocase; Transport; Ubiquinone
2 O75489 NDUFS3 NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial 264 3D-structure; Alternative splicing; Direct protein sequencing; Disease mutation; Electron transport; Membrane; Mitochondrion; Mitochondrion inner membrane; NAD; Oxidoreductase; Polymorphism; Primary mitochondrial disease; Reference proteome; Respiratory chain; Transit peptide; Translocase; Transport; Ubiquinone
2 Q8TD19 NEK9 Serine/threonine-protein kinase Nek9 979 3D-structure; ATP-binding; Acetylation; Cell cycle; Cell division; Coiled coil; Cytoplasm; Direct protein sequencing; Disease mutation; Kinase; Magnesium; Metal-binding; Mitosis; Nucleotide-binding; Nucleus; Phosphoprotein; Polymorphism; Reference proteome; Repeat; Serine/threonine-protein kinase; Transferase
1 P25208 NFYB Nuclear transcription factor Y subunit beta 207 3D-structure; Activator; DNA-binding; Isopeptide bond; Nucleus; Reference proteome; Transcription; Transcription regulation; Ubl conjugation
1 Q13952 NFYC Nuclear transcription factor Y subunit gamma 458 3D-structure; Activator; Alternative splicing; DNA-binding; Nucleus; Polymorphism; Reference proteome; Transcription; Transcription regulation
1 Q13287 NMI N-myc-interactor 307 Cytoplasm; Phosphoprotein; Polymorphism; Reference proteome
1 Q9Y3T9 NOC2L Nucleolar complex protein 2 homolog 749 Apoptosis; Nucleus; Phosphoprotein; Polymorphism; Reference proteome; Repressor; Transcription; Transcription regulation
1 Q9H8H0 NOL11 Nucleolar protein 11 719 Activator; Alternative splicing; Methylation; Nucleus; Polymorphism; Reference proteome; Ribosome biogenesis; Transcription; Transcription regulation; rRNA processing
1 Q5SY16 NOL9 Polynucleotide 5'-hydroxyl-kinase NOL9 702 ATP-binding; Acetylation; Isopeptide bond; Kinase; Nucleotide-binding; Nucleus; Phosphoprotein; Polymorphism; RNA-binding; Reference proteome; Transferase; Ubl conjugation; rRNA processing
3 Q15233 NONO Non-POU domain-containing octamer-binding protein 471 3D-structure; Acetylation; Activator; Alternative splicing; Biological rhythms; Chromosomal rearrangement; Coiled coil; DNA damage; DNA recombination; DNA repair; DNA-binding; Direct protein sequencing; Immunity; Innate immunity; Isopeptide bond; Mental retardation; Methylation; Nucleus; Phosphoprotein; RNA-binding; Reference proteome; Repeat; Repressor; Transcription; Transcription regulation; Ubl conjugation; mRNA processing; mRNA splicing
2 O00567 NOP56 Nucleolar protein 56 594 Acetylation; Cytoplasm; Direct protein sequencing; Isopeptide bond; Methylation; Neurodegeneration; Nucleus; Phosphoprotein; Polymorphism; Reference proteome; Ribonucleoprotein; Ribosome biogenesis; Spinocerebellar ataxia; Ubl conjugation
2 Q8WUM0 NUP133 Nuclear pore complex protein Nup133 1156 3D-structure; Acetylation; Centromere; Chromosome; Disease mutation; Epilepsy; Kinetochore; Mental retardation; Methylation; Nuclear pore complex; Nucleus; Phosphoprotein; Polymorphism; Protein transport; Reference proteome; Translocation; Transport; mRNA transport
1 Q5SRE5 NUP188 Nucleoporin NUP188 homolog 1749 3D-structure; Acetylation; Alternative splicing; Nuclear pore complex; Nucleus; Phosphoprotein; Polymorphism; Protein transport; Reference proteome; Translocation; Transport; mRNA transport
1 Q92621 NUP205 Nuclear pore complex protein Nup205 2012 3D-structure; Acetylation; Direct protein sequencing; Disease mutation; Membrane; Nuclear pore complex; Nucleus; Phosphoprotein; Polymorphism; Protein transport; Reference proteome; Translocation; Transport; mRNA transport
2 Q8N1F7 NUP93 Nuclear pore complex protein Nup93 819 3D-structure; Alternative splicing; Disease mutation; Membrane; Nuclear pore complex; Nucleus; Phosphoprotein; Polymorphism; Protein transport; Reference proteome; Translocation; Transport; mRNA transport
2 O60313 OPA1 Dynamin-like 120 kDa protein, mitochondrial 960 Acetylation; Alternative splicing; Apoptosis; Cardiomyopathy; Coiled coil; Deafness; Disease mutation; GTP-binding; Hydrolase; Lipid-binding; Membrane; Mitochondrion; Mitochondrion inner membrane; Neurodegeneration; Nucleotide-binding; Polymorphism; Primary mitochondrial disease; Reference proteome; Sensory transduction; Transit peptide; Transmembrane; Transmembrane helix; Vision
2 P13674 P4HA1 Prolyl 4-hydroxylase subunit alpha-1 534 3D-structure; Alternative splicing; Dioxygenase; Endoplasmic reticulum; Glycoprotein; Iron; Metal-binding; Oxidoreductase; Reference proteome; Signal; TPR repeat; Vitamin C
1 Q53GL7 PARP10 Protein mono-ADP-ribosyltransferase PARP10 1025 3D-structure; ADP-ribosylation; Acetylation; Cytoplasm; DNA damage; DNA repair; Glycosyltransferase; NAD; Nucleus; Phosphoprotein; Polymorphism; Reference proteome; Transferase
2 Q15365 PCBP1 Poly 356 3D-structure; Acetylation; Cytoplasm; DNA-binding; Direct protein sequencing; Isopeptide bond; Nucleus; Phosphoprotein; RNA-binding; Reference proteome; Repeat; Ribonucleoprotein; Ubl conjugation; Viral RNA replication
1 Q14690 PDCD11 Protein RRP5 homolog 1871 3D-structure; Acetylation; Direct protein sequencing; Isopeptide bond; Nucleus; Phosphoprotein; Polymorphism; Reference proteome; Repeat; Ubl conjugation; rRNA processing
1 Q29RF7 PDS5A Sister chromatid cohesion protein PDS5 homolog A 1337 Acetylation; Alternative splicing; Cell cycle; Cell division; Mitosis; Nucleus; Phosphoprotein; Polymorphism; Reference proteome; Repeat
User defined Q96DB6 PDS5A PDS5A protein 378
2 Q9NTI5 PDS5B Sister chromatid cohesion protein PDS5 homolog B 1447 3D-structure; Acetylation; Alternative splicing; Cell cycle; Cell division; Mitosis; Nucleus; Phosphoprotein; Reference proteome; Repeat
2 Q9BRX2 PELO Protein pelota homolog 385 3D-structure; Cell cycle; Cell division; Cytoplasm; Endonuclease; Hydrolase; Isopeptide bond; Metal-binding; Nuclease; Nucleus; Phosphoprotein; Polymorphism; Reference proteome; Ubl conjugation
1 Q99471 PFDN5 Prefoldin subunit 5 154 3D-structure; Acetylation; Alternative splicing; Chaperone; Cytoplasm; Nucleus; Phosphoprotein; Reference proteome
1 Q75T13 PGAP1 GPI inositol-deacylase 922 Alternative splicing; Disease mutation; Endoplasmic reticulum; Glycoprotein; Hydrolase; Membrane; Mental retardation; Protein transport; Reference proteome; Transmembrane; Transmembrane helix; Transport
3 O75928 PIAS2 E3 SUMO-protein ligase PIAS2 621 3D-structure; Alternative splicing; DNA-binding; Isopeptide bond; Metal-binding; Nucleus; Phosphoprotein; Polymorphism; Reference proteome; Transcription; Transcription regulation; Transferase; Ubl conjugation; Ubl conjugation pathway; Zinc; Zinc-finger
2 P53350 PLK1 Serine/threonine-protein kinase PLK1 603 3D-structure; ATP-binding; Acetylation; Cell cycle; Cell division; Centromere; Chromosome; Cytoplasm; Cytoskeleton; Isopeptide bond; Kinase; Kinetochore; Mitosis; Nucleotide-binding; Nucleus; Phosphoprotein; Polymorphism; Reference proteome; Repeat; Serine/threonine-protein kinase; Transferase; Ubl conjugation
2 O60568 PLOD3 Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3 [Includes: Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3 738 3D-structure; Dioxygenase; Disease mutation; Disulfide bond; Endoplasmic reticulum; Glycoprotein; Glycosyltransferase; Iron; Manganese; Membrane; Metal-binding; Multifunctional enzyme; Oxidoreductase; Polymorphism; Reference proteome; Secreted; Signal; Transferase; Vitamin C
2 P29590 PML Protein PML 882 3D-structure; Acetylation; Activator; Alternative splicing; Antiviral defense; Apoptosis; Biological rhythms; Chromosomal rearrangement; Coiled coil; Cytoplasm; DNA-binding; Endoplasmic reticulum; Endosome; Host-virus interaction; Immunity; Innate immunity; Isopeptide bond; Membrane; Metal-binding; Nucleus; Phosphoprotein; Polymorphism; Proto-oncogene; Reference proteome; Repeat; Transcription; Transcription regulation; Tumor suppressor; Ubl conjugation; Zinc; Zinc-finger
2 P28340 POLD1 DNA polymerase delta catalytic subunit 1107 3D-structure; 4Fe-4S; DNA damage; DNA excision; DNA repair; DNA replication; DNA-binding; DNA-directed DNA polymerase; Disease mutation; Exonuclease; Hydrolase; Iron; Iron-sulfur; Isopeptide bond; Metal-binding; Methylation; Nuclease; Nucleotidyltransferase; Nucleus; Polymorphism; Reference proteome; Transferase; Ubl conjugation; Zinc; Zinc-finger
2 Q07864 POLE DNA polymerase epsilon catalytic subunit A 2286 3D-structure; 4Fe-4S; DNA damage; DNA repair; DNA replication; DNA-binding; DNA-directed DNA polymerase; Direct protein sequencing; Disease mutation; Hydrolase; Iron; Iron-sulfur; Metal-binding; Nucleotidyltransferase; Nucleus; Phosphoprotein; Polymorphism; Reference proteome; Transferase; Zinc; Zinc-finger
1 O95602 POLR1A DNA-directed RNA polymerase I subunit RPA1 1720 3D-structure; Chromosome; Disease variant; DNA-directed RNA polymerase; Magnesium; Metal-binding; Nucleotidyltransferase; Nucleus; Phosphoprotein; Reference proteome; Transcription; Transferase; Zinc;
4 P24928 POLR2A DNA-directed RNA polymerase II subunit RPB1 1970 3D-structure; Acetylation; Alternative splicing; Chromosome; Cytoplasm; DNA-binding; DNA-directed RNA polymerase; Disease mutation; Host-virus interaction; Magnesium; Mental retardation; Metal-binding; Methylation; Nucleotidyltransferase; Nucleus; Phosphoprotein; Polymorphism; RNA-directed RNA polymerase; Reference proteome; Repeat; Transcription; Transferase; Ubl conjugation; Zinc
2 P30876 POLR2B DNA-directed RNA polymerase II subunit RPB2 1174 3D-structure; DNA-directed RNA polymerase; Hydrolase; Magnesium; Metal-binding; Methylation; Nucleotidyltransferase; Nucleus; Phosphoprotein; Reference proteome; RNA-directed RNA polymerase; Transcription; Transferase; Zinc; Zinc-finger;
2 P62136 PPP1CA Serine/threonine-protein phosphatase PP1-alpha catalytic subunit 330 3D-structure; Acetylation; Alternative splicing; Carbohydrate metabolism; Cell cycle; Cell division; Cytoplasm; Direct protein sequencing; Glycogen metabolism; Host-virus interaction; Hydrolase; Manganese; Metal-binding; Nucleus; Phosphoprotein; Protein phosphatase; Reference proteome
2 O00743 PPP6C Serine/threonine-protein phosphatase 6 catalytic subunit 305 Acetylation; Alternative splicing; Cell cycle; Cytoplasm; Direct protein sequencing; Hydrolase; Immunity; Innate immunity; Manganese; Metal-binding; Mitochondrion; Protein phosphatase; Reference proteome
2 P50897 PPT1 Palmitoyl-protein thioesterase 1 306 3D-structure; Alternative splicing; Disease mutation; Disulfide bond; Glycoprotein; Hydrolase; Lysosome; Neurodegeneration; Neuronal ceroid lipofuscinosis; Polymorphism; Reference proteome; Secreted; Sensory transduction; Signal; Vision
1 Q06830 PRDX1 Peroxiredoxin-1 199 3D-structure; Acetylation; Antioxidant; Cytoplasm; Direct protein sequencing; Disulfide bond; Isopeptide bond; Oxidoreductase; Peroxidase; Phosphoprotein; Polymorphism; Redox-active center; Reference proteome; Ubl conjugation
2 P78527 PRKDC DNA-dependent protein kinase catalytic subunit 4128 3D-structure; ATP-binding; Acetylation; Alternative splicing; Biological rhythms; DNA damage; DNA recombination; DNA repair; DNA-binding; Disease mutation; Immunity; Innate immunity; Kinase; Nucleotide-binding; Nucleus; Phosphoprotein; Polymorphism; Reference proteome; Repeat; Ribosome biogenesis; SCID; Serine/threonine-protein kinase; TPR repeat; Transferase; Ubl conjugation
3 O94906 PRPF6 Pre-mRNA-processing factor 6 941 3D-structure; Alternative splicing; Direct protein sequencing; Disease mutation; Nucleus; Phosphoprotein; Polymorphism; Reference proteome; Repeat; Retinitis pigmentosa; Spliceosome; mRNA processing; mRNA splicing
2 Q6P2Q9 PRPF8 Pre-mRNA-processing-splicing factor 8 2335 3D-structure; Acetylation; Direct protein sequencing; Disease mutation; Methylation; Nucleus; Phosphoprotein; Polymorphism; RNA-binding; Reference proteome; Retinitis pigmentosa; Ribonucleoprotein; Spliceosome; mRNA processing; mRNA splicing
3 P25786 PSMA1 Proteasome subunit alpha type-1 263 3D-structure; Acetylation; Alternative splicing; Cytoplasm; Direct protein sequencing; Glycoprotein; Hydrolase; Immunity; Isopeptide bond; Nucleus; Phosphoprotein; Polymorphism; Protease; Proteasome; Reference proteome; Threonine protease; Ubl conjugation
4 P25788 PSMA3 Proteasome subunit alpha type-3 255 3D-structure; Acetylation; Alternative splicing; Cytoplasm; Direct protein sequencing; Host-virus interaction; Hydrolase; Nucleus; Phosphoprotein; Polymorphism; Protease; Proteasome; Reference proteome; Threonine protease
2 P25789 PSMA4 Proteasome subunit alpha type-4 261 3D-structure; Acetylation; Alternative splicing; Cytoplasm; Direct protein sequencing; Host-virus interaction; Hydrolase; Nucleus; Phosphoprotein; Protease; Proteasome; Reference proteome; Threonine protease
2 P28066 PSMA5 Proteasome subunit alpha type-5 241 3D-structure; Acetylation; Alternative splicing; Cytoplasm; Direct protein sequencing; Glycoprotein; Hydrolase; Nucleus; Phosphoprotein; Protease; Proteasome; Reference proteome; Threonine protease
2 O14818 PSMA7 Proteasome subunit alpha type-7 248 3D-structure; Acetylation; Alternative splicing; Cytoplasm; Direct protein sequencing; Glycoprotein; Host-virus interaction; Hydrolase; Nucleus; Phosphoprotein; Polymorphism; Protease; Proteasome; Reference proteome; Threonine protease
2 P20618 PSMB1 Proteasome subunit beta type-1 241 3D-structure; Acetylation; Cytoplasm; Direct protein sequencing; Glycoprotein; Host-virus interaction; Hydrolase; Nucleus; Phosphoprotein; Polymorphism; Protease; Proteasome; Reference proteome; Threonine protease
2 P49720 PSMB3 Proteasome subunit beta type-3 205 3D-structure; Acetylation; Cytoplasm; Direct protein sequencing; Host-virus interaction; Hydrolase; Nucleus; Polymorphism; Protease; Proteasome; Reference proteome; Threonine protease
2 P28070 PSMB4 Proteasome subunit beta type-4 264 3D-structure; Acetylation; Cytoplasm; Direct protein sequencing; Disease mutation; Host-virus interaction; Hydrolase; Nucleus; Phosphoprotein; Polymorphism; Protease; Proteasome; Reference proteome; Threonine protease; Zymogen
2 P28074 PSMB5 Proteasome subunit beta type-5 263 3D-structure; Alternative splicing; Cytoplasm; Direct protein sequencing; Host-virus interaction; Hydrolase; Nucleus; Polymorphism; Protease; Proteasome; Reference proteome; Threonine protease; Zymogen
User defined Q53XL8 PSMC1 Proteasome 440 ATP-binding; Nucleotide-binding; Proteasome
2 P35998 PSMC2 26S proteasome regulatory subunit 7 433 3D-structure; ATP-binding; Acetylation; Alternative splicing; Cytoplasm; Direct protein sequencing; Nucleotide-binding; Proteasome; Reference proteome
2 P17980 PSMC3 26S proteasome regulatory subunit 6A 439 3D-structure; ATP-binding; Acetylation; Cytoplasm; Direct protein sequencing; Host-virus interaction; Nucleotide-binding; Nucleus; Phosphoprotein; Proteasome; Reference proteome; Ubl conjugation
2 P43686 PSMC4 26S proteasome regulatory subunit 6B 418 3D-structure; ATP-binding; Acetylation; Alternative splicing; Cytoplasm; Direct protein sequencing; Nucleotide-binding; Nucleus; Phosphoprotein; Proteasome; Reference proteome
2 P62333 PSMC6 26S proteasome regulatory subunit 10B 389 3D-structure; ATP-binding; Acetylation; Cytoplasm; Direct protein sequencing; Nucleotide-binding; Nucleus; Phosphoprotein; Proteasome; Reference proteome
4 Q13200 PSMD2 26S proteasome non-ATPase regulatory subunit 2 908 3D-structure; Acetylation; Alternative splicing; Direct protein sequencing; Phosphoprotein; Polymorphism; Proteasome; Reference proteome; Repeat
2 O43242 PSMD3 26S proteasome non-ATPase regulatory subunit 3 534 3D-structure; Alternative splicing; Isopeptide bond; Phosphoprotein; Proteasome; Reference proteome; Ubl conjugation
2 P55036 PSMD4 26S proteasome non-ATPase regulatory subunit 4 377 3D-structure; Alternative splicing; Direct protein sequencing; Isopeptide bond; Phosphoprotein; Proteasome; Reference proteome; Repeat; Ubl conjugation
2 Q14997 PSME4 Proteasome activator complex subunit 4 1843 3D-structure; Alternative splicing; Cytoplasm; DNA damage; DNA repair; Developmental protein; Differentiation; Nucleus; Phosphoprotein; Polymorphism; Proteasome; Reference proteome; Repeat; Spermatogenesis
2 Q9H7Z7 PTGES2 Prostaglandin E synthase 2 377 Cytoplasm; Fatty acid biosynthesis; Fatty acid metabolism; Golgi apparatus; Isomerase; Lipid biosynthesis; Lipid metabolism; Membrane; Phosphoprotein; Polymorphism; Prostaglandin biosynthesis; Prostaglandin metabolism; Reference proteome; Transmembrane; Transmembrane helix
3 Q15678 PTPN14 Tyrosine-protein phosphatase non-receptor type 14 1187 3D-structure; Cytoplasm; Cytoskeleton; Hydrolase; Nucleus; Phosphoprotein; Polymorphism; Protein phosphatase; Reference proteome; Transcription; Transcription regulation; Ubl conjugation
User defined Q05CG6 Q05CG6 Q05CG6
User defined Q4ZG48 Q4ZG48 Q4ZG48
User defined Q5JSV6 Q5JSV6 Q5JSV6
User defined Q5T9I7 Q5T9I7 Q5T9I7
User defined Q6IAV9 Q6IAV9 Q6IAV9
User defined Q6ICS6 Q6ICS6 Q6ICS6
User defined Q6NZY0 Q6NZY0 Q6NZY0
User defined Q8WUM8 Q8WUM8 Q8WUM8
User defined Q8WVK4 Q8WVK4 Q8WVK4
User defined Q96AM8 Q96AM8 Q96AM8
User defined Q96BC0 Q96BC0 Q96BC0
User defined Q96DP1 Q96DP1 Q96DP1
User defined Q96IX6 Q96IX6 Q96IX6
User defined Q96L91-2 Q96L91-2 Q96L91-2
User defined Q96Q14 Q96Q14 Q96Q14
User defined Q99651 Q99651 Q99651
User defined Q9BZQ1 Q9BZQ1 Q9BZQ1
User defined Q9H023 Q9H023 Q9H023
User defined Q9ULN3 Q9ULN3 Q9ULN3
User defined Q9UNJ2 Q9UNJ2 Q9UNJ2
3 P04049 RAF1 RAF proto-oncogene serine/threonine-protein kinase 648 3D-structure; ATP-binding; Alternative splicing; Cardiomyopathy; Cell membrane; Cytoplasm; Deafness; Direct protein sequencing; Disease mutation; Kinase; Membrane; Metal-binding; Methylation; Mitochondrion; Nucleotide-binding; Nucleus; Phosphoprotein; Polymorphism; Proto-oncogene; Reference proteome; Serine/threonine-protein kinase; Transferase; Zinc; Zinc-finger
2 P49792 RANBP2 E3 SUMO-protein ligase RanBP2 3224 3D-structure; Acetylation; Chromosomal rearrangement; Disulfide bond; Isopeptide bond; Membrane; Metal-binding; Methylation; Nuclear pore complex; Nucleus; Phosphoprotein; Polymorphism; Protein transport; RNA-binding; Reference proteome; Repeat; TPR repeat; Transferase; Translocation; Transport; Ubl conjugation; Ubl conjugation pathway; Zinc; Zinc-finger; mRNA transport
1 P06400 RB1 Retinoblastoma-associated protein 928 3D-structure; Acetylation; Cell cycle; Chromatin regulator; DNA-binding; Direct protein sequencing; Disease mutation; Host-virus interaction; Methylation; Nucleus; Phosphoprotein; Polymorphism; Reference proteome; Repressor; Transcription; Transcription regulation; Tumor suppressor
1 P28749 RBL1 Retinoblastoma-like protein 1 1068 3D-structure; Alternative splicing; Cell cycle; Chromatin regulator; Direct protein sequencing; Host-virus interaction; Nucleus; Phosphoprotein; Polymorphism; Reference proteome; Repressor; Transcription; Transcription regulation; Tumor suppressor
1 Q04206 RELA Transcription factor p65 551 3D-structure; Acetylation; Activator; Alternative splicing; Chromosomal rearrangement; Cytoplasm; DNA-binding; Disease mutation; Host-virus interaction; Isopeptide bond; Methylation; Nucleus; Phosphoprotein; Reference proteome; S-nitrosylation; Transcription; Transcription regulation; Ubl conjugation
1 P35251 RFC1 Replication factor C subunit 1 1148 3D-structure; ATP-binding; Activator; Alternative splicing; DNA replication; DNA-binding; Direct protein sequencing; Isopeptide bond; Neuropathy; Nucleotide-binding; Nucleus; Phosphoprotein; Polymorphism; Reference proteome; Transcription; Transcription regulation; Ubl conjugation
2 P35250 RFC2 Replication factor C subunit 2 354 3D-structure; ATP-binding; Acetylation; Alternative splicing; DNA replication; Direct protein sequencing; Nucleotide-binding; Nucleus; Phosphoprotein; Polymorphism; Reference proteome; Williams-Beuren syndrome
3 P40938 RFC3 Replication factor C subunit 3 356 3D-structure; Acetylation; Alternative splicing; DNA replication; DNA-binding; Nucleus; Phosphoprotein; Polymorphism; Reference proteome
2 P35249 RFC4 Replication factor C subunit 4 363 3D-structure; ATP-binding; Acetylation; Alternative splicing; DNA replication; Direct protein sequencing; Nucleotide-binding; Nucleus; Polymorphism; Reference proteome
2 P40937 RFC5 Replication factor C subunit 5 340 3D-structure; ATP-binding; Acetylation; Alternative splicing; DNA replication; Nucleotide-binding; Nucleus; Polymorphism; Reference proteome
1 Q8IUF8 RIOX2 Ribosomal oxygenase 2 465 3D-structure; Alternative splicing; Dioxygenase; Iron; Metal-binding; Nucleus; Oxidoreductase; Phosphoprotein; Polymorphism; Reference proteome; Ribosome biogenesis; Transcription; Transcription regulation
2 P13489 RNH1 Ribonuclease inhibitor 461 3D-structure; Acetylation; Cytoplasm; Direct protein sequencing; Leucine-rich repeat; Phosphoprotein; Polymorphism; Reference proteome; Repeat
1 P62913 RPL11 60S ribosomal protein L11 178 3D-structure; Acetylation; Alternative splicing; Cytoplasm; Diamond-Blackfan anemia; Direct protein sequencing; Disease mutation; Isopeptide bond; Nucleus; Phosphoprotein; RNA-binding; Reference proteome; Ribonucleoprotein; Ribosomal protein; Ubl conjugation; rRNA-binding
2 P04843 RPN1 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 607 3D-structure; Acetylation; Endoplasmic reticulum; Glycoprotein; Isopeptide bond; Membrane; Reference proteome; Signal; Transmembrane; Transmembrane helix; Ubl conjugation
2 P04844 RPN2 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 631 3D-structure; Alternative splicing; Direct protein sequencing; Endoplasmic reticulum; Glycoprotein; Isopeptide bond; Membrane; Polymorphism; Reference proteome; Signal; Transmembrane; Transmembrane helix; Ubl conjugation
3 P78346 RPP30 Ribonuclease P protein subunit p30 268 3D-structure; Acetylation; Alternative splicing; Direct protein sequencing; Hydrolase; Nucleus; Phosphoprotein; Polymorphism; RNA-binding; Reference proteome; rRNA processing; tRNA processing
2 Q9Y265 RUVBL1 RuvB-like 1 456 3D-structure; ATP-binding; Acetylation; Activator; Alternative splicing; Cell cycle; Cell division; Chromatin regulator; Cytoplasm; Cytoskeleton; DNA damage; DNA recombination; DNA repair; Direct protein sequencing; Growth regulation; Helicase; Hydrolase; Isopeptide bond; Membrane; Mitosis; Nucleotide-binding; Nucleus; Reference proteome; Transcription; Transcription regulation; Ubl conjugation
2 Q9Y230 RUVBL2 RuvB-like 2 463 3D-structure; ATP-binding; Acetylation; Activator; Alternative splicing; Chromatin regulator; Cytoplasm; DNA damage; DNA recombination; DNA repair; Direct protein sequencing; Growth regulation; Helicase; Hydrolase; Isopeptide bond; Membrane; Nucleotide-binding; Nucleus; Phosphoprotein; Reference proteome; Transcription; Transcription regulation; Ubl conjugation
2 P49591 SARS1 Serine--tRNA ligase, cytoplasmic 514 3D-structure; ATP-binding; Acetylation; Aminoacyl-tRNA synthetase; Cytoplasm; DNA-binding; Disease mutation; Epilepsy; Ligase; Mental retardation; Nucleotide-binding; Nucleus; Phosphoprotein; Protein biosynthesis; Reference proteome; Transcription; Transcription regulation
1 P61619 SEC61A1 Protein transport protein Sec61 subunit alpha isoform 1 476 Alternative splicing; Disease mutation; Endoplasmic reticulum; Membrane; Protein transport; Reference proteome; Translocation; Transmembrane; Transmembrane helix; Transport
1 Q15393 SF3B3 Splicing factor 3B subunit 3 1217 3D-structure; Alternative splicing; Direct protein sequencing; Nucleus; Phosphoprotein; Polymorphism; Reference proteome; Spliceosome; mRNA processing; mRNA splicing
2 Q9UQ13 SHOC2 Leucine-rich repeat protein SHOC-2 582 Alternative splicing; Cytoplasm; Disease mutation; Leucine-rich repeat; Nucleus; Reference proteome; Repeat
3 P63208 SKP1 S-phase kinase-associated protein 1 163 3D-structure; Alternative splicing; Direct protein sequencing; Host-virus interaction; Isopeptide bond; Phosphoprotein; Reference proteome; Ubl conjugation; Ubl conjugation pathway;
1 Q13309 SKP2 S-phase kinase-associated protein 2 424 3D-structure; Acetylation; Alternative splicing; Antiviral defense; Cytoplasm; Direct protein sequencing; Host-virus interaction; Immunity; Innate immunity; Leucine-rich repeat; Nucleus; Phosphoprotein; Polymorphism; Reference proteome; Repeat; Ubl conjugation; Ubl conjugation pathway
2 P53007 SLC25A1 Tricarboxylate transport protein, mitochondrial 311 Congenital myasthenic syndrome; Disease mutation; Membrane; Mitochondrion; Mitochondrion inner membrane; Phosphoprotein; Reference proteome; Repeat; Transit peptide; Transmembrane; Transmembrane helix; Transport
2 Q02978 SLC25A11 Mitochondrial 2-oxoglutarate/malate carrier protein 314 Acetylation; Alternative splicing; Direct protein sequencing; Disease mutation; Membrane; Mitochondrion; Mitochondrion inner membrane; Phosphoprotein; Reference proteome; Repeat; Transmembrane; Transmembrane helix; Transport
3 Q9UJS0 SLC25A13 Calcium-binding mitochondrial carrier protein Aralar2 675 3D-structure; Acetylation; Alternative splicing; Calcium; Disease mutation; Intrahepatic cholestasis; Membrane; Metal-binding; Methylation; Mitochondrion; Mitochondrion inner membrane; Phosphoprotein; Polymorphism; Reference proteome; Repeat; Transmembrane; Transmembrane helix; Transport
2 O94813 SLIT2 Slit homolog 2 protein 1529 3D-structure; Alternative splicing; Chemotaxis; Developmental protein; Differentiation; Direct protein sequencing; Disulfide bond; EGF-like domain; Glycoprotein; Heparin-binding; Leucine-rich repeat; Neurogenesis; Polymorphism; Reference proteome; Repeat; Secreted; Signal
1 Q15796 SMAD2 Mothers against decapentaplegic homolog 2 467 3D-structure; Acetylation; Alternative splicing; Cytoplasm; DNA-binding; Direct protein sequencing; Metal-binding; Nucleus; Phosphoprotein; Polymorphism; Reference proteome; Transcription; Transcription regulation; Ubl conjugation; Zinc
1 P84022 SMAD3 Mothers against decapentaplegic homolog 3 425 3D-structure; ADP-ribosylation; Acetylation; Alternative splicing; Aortic aneurysm; Cytoplasm; DNA-binding; Disease mutation; Host-virus interaction; Isopeptide bond; Metal-binding; Nucleus; Phosphoprotein; Polymorphism; Reference proteome; Transcription; Transcription regulation; Ubl conjugation; Zinc
1 P51532 SMARCA4 Transcription activator BRG1 1647 3D-structure; Acetylation; Activator; Alternative splicing; ATP-binding; Bromodomain; Chromatin regulator; Disease variant; Helicase; Hydrolase; Intellectual disability; Isopeptide bond; Neurogenesis; Nucleotide-binding; Nucleus; Phosphoprotein; Reference proteome; Repressor; RNA-binding; Transcription; Transcription regulation; Ubl conjugation;
4 O60264 SMARCA5 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 1052 3D-structure; ATP-binding; Acetylation; Chromatin regulator; Helicase; Hydrolase; Isopeptide bond; Nucleotide-binding; Nucleus; Phosphoprotein; Reference proteome; Repeat; Ubl conjugation
1 Q9H4L7 SMARCAD1 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 1026 3D-structure; ATP-binding; Acetylation; Alternative splicing; Chromatin regulator; Chromosome; DNA damage; DNA repair; DNA-binding; Ectodermal dysplasia; Helicase; Hydrolase; Isopeptide bond; Nucleotide-binding; Nucleus; Palmoplantar keratoderma; Phosphoprotein; Polymorphism; Reference proteome; Repeat; Ubl conjugation
1 Q12824 SMARCB1 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 385 3D-structure; Activator; Alternative splicing; Cell cycle; Chromatin regulator; DNA-binding; Disease mutation; Host-virus interaction; Hypotrichosis; Isopeptide bond; Mental retardation; Neurogenesis; Nucleus; Phosphoprotein; Reference proteome; Repeat; Transcription; Transcription regulation; Tumor suppressor; Ubl conjugation
2 Q92922 SMARCC1 SWI/SNF complex subunit SMARCC1 1105 3D-structure; Acetylation; Chromatin regulator; Coiled coil; Cytoplasm; Direct protein sequencing; Isopeptide bond; Methylation; Neurogenesis; Nucleus; Phosphoprotein; Polymorphism; Reference proteome; Transcription; Transcription regulation; Ubl conjugation
1 Q8TAQ2 SMARCC2 SWI/SNF complex subunit SMARCC2 1214 3D-structure; Acetylation; Alternative splicing; Chromatin regulator; Coiled coil; Disease mutation; Isopeptide bond; Mental retardation; Neurogenesis; Nucleus; Phosphoprotein; Reference proteome; Transcription; Transcription regulation; Ubl conjugation
1 Q14683 SMC1A Structural maintenance of chromosomes protein 1A 1233 ATP-binding; Acetylation; Cell cycle; Cell division; Centromere; Chromosome; Coiled coil; DNA damage; DNA repair; Direct protein sequencing; Disease mutation; Kinetochore; Meiosis; Mental retardation; Mitosis; Nucleotide-binding; Nucleus; Phosphoprotein; Polymorphism; Reference proteome; Ubl conjugation
2 O95347 SMC2 Structural maintenance of chromosomes protein 2 1197 3D-structure; Acetylation; Alternative splicing; ATP-binding; Cell cycle; Cell division; Chromosome; Coiled coil; Cytoplasm; DNA condensation; Mitosis; Nucleotide-binding; Nucleus; Reference proteome;
1 Q9UQE7 SMC3 Structural maintenance of chromosomes protein 3 1217 3D-structure; Acetylation; ATP-binding; Cell cycle; Cell division; Centromere; Chromosome; Coiled coil; Direct protein sequencing; Disease variant; DNA damage; DNA repair; Intellectual disability; Meiosis; Mitosis; Nucleotide-binding; Nucleus; Phosphoprotein; Reference proteome; Ubl conjugation;
3 Q9NTJ3 SMC4 Structural maintenance of chromosomes protein 4 1288 3D-structure; ATP-binding; Acetylation; Alternative splicing; Cell cycle; Cell division; Chromosome; Coiled coil; Cytoplasm; DNA condensation; Mitosis; Nucleotide-binding; Nucleus; Phosphoprotein; Polymorphism; Reference proteome
2 Q8TAD8 SNIP1 Smad nuclear-interacting protein 1 396 3D-structure; Coiled coil; Disease mutation; Epilepsy; Isopeptide bond; Nucleus; Phosphoprotein; RNA-mediated gene silencing; Reference proteome; Spliceosome; Ubl conjugation; mRNA processing; mRNA splicing
2 O75643 SNRNP200 U5 small nuclear ribonucleoprotein 200 kDa helicase 2136 3D-structure; ATP-binding; Acetylation; Alternative splicing; Coiled coil; Direct protein sequencing; Disease mutation; Helicase; Hydrolase; Isopeptide bond; Nucleotide-binding; Nucleus; Phosphoprotein; Polymorphism; Reference proteome; Repeat; Retinitis pigmentosa; Spliceosome; Ubl conjugation; mRNA processing; mRNA splicing
4 P08047 SP1 Transcription factor Sp1 785 3D-structure; Acetylation; Activator; Alternative splicing; Biological rhythms; Cytoplasm; DNA-binding; Direct protein sequencing; Glycoprotein; Host-virus interaction; Isopeptide bond; Metal-binding; Nucleus; Phosphoprotein; Polymorphism; Reference proteome; Repeat; Repressor; Transcription; Transcription regulation; Ubl conjugation; Zinc; Zinc-finger
1 O60271 SPAG9 C-Jun-amino-terminal kinase-interacting protein 4 1321 3D-structure; Acetylation; Alternative splicing; Coiled coil; Cytoplasm; Cytoplasmic vesicle; Lysosome; Membrane; Phosphoprotein; Polymorphism; Reference proteome
3 Q9Y6N5 SQOR Sulfide:quinone oxidoreductase, mitochondrial 450 3D-structure; Acetylation; Disulfide bond; FAD; Flavoprotein; Mitochondrion; Oxidoreductase; Phosphoprotein; Polymorphism; Quinone; Reference proteome; Transit peptide
2 Q13501 SQSTM1 Sequestosome-1 440 3D-structure; Acetylation; Alternative splicing; Amyotrophic lateral sclerosis; Apoptosis; Autophagy; Cytoplasm; Cytoplasmic vesicle; Differentiation; Direct protein sequencing; Disease mutation; Endoplasmic reticulum; Endosome; Immunity; Isopeptide bond; Lysosome; Metal-binding; Neurodegeneration; Nucleus; Phosphoprotein; Polymorphism; Reference proteome; Ubl conjugation; Zinc; Zinc-finger
2 P51571 SSR4 Translocon-associated protein subunit delta 173 Congenital disorder of glycosylation; Disulfide bond; Endoplasmic reticulum; Isopeptide bond; Membrane; Polymorphism; Reference proteome; Signal; Transmembrane; Transmembrane helix; Ubl conjugation
1 Q8N3U4 STAG2 Cohesin subunit SA-2 1231 3D-structure; Acetylation; Alternative splicing; Cell cycle; Cell division; Centromere; Chromosome; Chromosome partition; Disease mutation; Meiosis; Mitosis; Nucleus; Phosphoprotein; Polymorphism; Reference proteome
3 P53597 SUCLG1 Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial 346 3D-structure; Acetylation; Disease mutation; Ligase; Mitochondrion; Nucleotide-binding; Polymorphism; Primary mitochondrial disease; Reference proteome; Transit peptide; Tricarboxylic acid cycle
1 O75486 SUPT3H Transcription initiation protein SPT3 homolog 317 Acetylation; Activator; Alternative splicing; Direct protein sequencing; Isopeptide bond; Nucleus; Polymorphism; Reference proteome; Transcription; Transcription regulation; Ubl conjugation
1 O75478 TADA2A Transcriptional adapter 2-alpha 443 3D-structure; Alternative splicing; Chromosome; DNA-binding; Isopeptide bond; Nucleus; Phosphoprotein; Polymorphism; Reference proteome; Transcription; Transcription regulation; Ubl conjugation
1 O75528 TADA3 Transcriptional adapter 3 432 Acetylation; Alternative splicing; Coiled coil; Isopeptide bond; Nucleus; Phosphoprotein; Reference proteome; Transcription; Transcription regulation; Ubl conjugation
1 Q12962 TAF10 Transcription initiation factor TFIID subunit 10 218 3D-structure; Acetylation; Direct protein sequencing; Methylation; Nucleus; Phosphoprotein; Polymorphism; Reference proteome; Transcription; Transcription regulation
1 Q16514 TAF12 Transcription initiation factor TFIID subunit 12 161 3D-structure; Alternative initiation; Direct protein sequencing; Isopeptide bond; Nucleus; Phosphoprotein; Reference proteome; Transcription; Transcription regulation; Ubl conjugation
1 Q53T94 TAF1B TATA box-binding protein-associated factor RNA polymerase I subunit B 588 Acetylation; Alternative splicing; DNA-binding; Direct protein sequencing; Metal-binding; Nucleus; Polymorphism; Reference proteome; Transcription; Transcription regulation; Zinc; Zinc-finger
User defined Q15542 TAF5 Transcription initiation factor TFIID subunit 5 800 3D-structure; Alternative splicing; Direct protein sequencing; Host-virus interaction; Nucleus; Polymorphism; Reference proteome; Repeat; Transcription; Transcription regulation; WD repeat
1 O75529 TAF5L TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L 589 Alternative splicing; Direct protein sequencing; Nucleus; Reference proteome; Repeat; Transcription; Transcription regulation; WD repeat
1 Q9Y6J9 TAF6L TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L 622 Direct protein sequencing; Methylation; Nucleus; Phosphoprotein; Reference proteome; Transcription; Transcription regulation
1 Q16594 TAF9 Transcription initiation factor TFIID subunit 9 264 3D-structure; Acetylation; DNA-binding; Direct protein sequencing; Nucleus; Phosphoprotein; Polymorphism; Reference proteome; Transcription; Transcription regulation
1 P20226 TBP TATA-box-binding protein 339 3D-structure; Alternative splicing; Disease variant; DNA-binding; Host-virus interaction; Neurodegeneration; Nucleus; Reference proteome; Repeat; Spinocerebellar ataxia; Transcription; Transcription regulation; Triplet repeat expansion;
3 P17987 TCP1 T-complex protein 1 subunit alpha 556 3D-structure; Acetylation; ATP-binding; Chaperone; Cytoplasm; Cytoskeleton; Direct protein sequencing; Nucleotide-binding; Phosphoprotein; Reference proteome;
1 P05549 TFAP2A Transcription factor AP-2-alpha 437 Activator; Alternative splicing; DNA-binding; Direct protein sequencing; Disease mutation; Isopeptide bond; Nucleus; Phosphoprotein; Reference proteome; Transcription; Transcription regulation; Ubl conjugation
1 Q92481 TFAP2B Transcription factor AP-2-beta 460 Activator; Alternative splicing; DNA-binding; Disease mutation; Isopeptide bond; Nucleus; Phosphoprotein; Reference proteome; Transcription; Transcription regulation; Ubl conjugation
1 Q13009 TIAM1 T-lymphoma invasion and metastasis-inducing protein 1 1591 3D-structure; Alternative splicing; Cell junction; Cell membrane; Guanine-nucleotide releasing factor; Lipid-binding; Lipoprotein; Membrane; Myristate; Phosphoprotein; Polymorphism; Reference proteome; Repeat
1 P57088 TMEM33 Transmembrane protein 33 247 Acetylation; Endoplasmic reticulum; Immunity; Innate immunity; Membrane; Nucleus; Reference proteome; Transmembrane; Transmembrane helix;
2 P42166 TMPO Lamina-associated polypeptide 2, isoform alpha 694 3D-structure; Acetylation; Alternative splicing; Cardiomyopathy; Chromosome; Coiled coil; DNA-binding; Direct protein sequencing; Methylation; Nucleus; Pharmaceutical; Phosphoprotein; Polymorphism; Reference proteome
1 Q9Y5L0 TNPO3 Transportin-3 923 3D-structure; Acetylation; Alternative splicing; Cytoplasm; Disease mutation; Limb-girdle muscular dystrophy; Nucleus; Phosphoprotein; Protein transport; Reference proteome; Transport
2 P11387 TOP1 DNA topoisomerase 1 765 3D-structure; Acetylation; Biological rhythms; Chromosomal rearrangement; DNA-binding; Direct protein sequencing; Host-virus interaction; Isomerase; Isopeptide bond; Nucleus; Phosphoprotein; Polymorphism; Proto-oncogene; Reference proteome; Topoisomerase; Ubl conjugation
2 P11388 TOP2A DNA topoisomerase 2-alpha 1531 3D-structure; ATP-binding; Acetylation; Alternative splicing; Biological rhythms; Cytoplasm; DNA-binding; Direct protein sequencing; Isomerase; Isopeptide bond; Magnesium; Metal-binding; Nucleotide-binding; Nucleus; Phosphoprotein; Polymorphism; Reference proteome; Topoisomerase; Ubl conjugation
1 O15350 TP73 Tumor protein p73 636 3D-structure; Activator; Alternative promoter usage; Alternative splicing; Apoptosis; Cell cycle; Ciliopathy; Cytoplasm; Disease variant; DNA-binding; Host-virus interaction; Isopeptide bond; Lissencephaly; Metal-binding; Nucleus; Phosphoprotein; Primary ciliary dyskinesia; Reference proteome; Transcription; Transcription regulation; Tumor suppressor; Ubl conjugation; Zinc;
2 Q13263 TRIM28 Transcription intermediary factor 1-beta 835 3D-structure; Acetylation; Alternative splicing; Chromatin regulator; Citrullination; Coiled coil; Direct protein sequencing; Host-virus interaction; Isopeptide bond; Metal-binding; Nucleus; Phosphoprotein; Polymorphism; Reference proteome; Repeat; Repressor; Transcription; Transcription regulation; Transferase; Ubl conjugation; Ubl conjugation pathway; Zinc; Zinc-finger
3 Q9Y4A5 TRRAP Transformation/transcription domain-associated protein 3859 Acetylation; Activator; Alternative splicing; Autism spectrum disorder; Chromatin regulator; Direct protein sequencing; Disease mutation; Isopeptide bond; Mental retardation; Nucleus; Phosphoprotein; Polymorphism; Reference proteome; Transcription; Transcription regulation; Ubl conjugation
2 Q6P3X3 TTC27 Tetratricopeptide repeat protein 27 843 Polymorphism; Reference proteome; Repeat; TPR repeat
1 Q71U36 TUBA1A Tubulin alpha-1A chain 451 3D-structure; Acetylation; Alternative splicing; Cytoplasm; Cytoskeleton; Direct protein sequencing; Disease mutation; GTP-binding; Isopeptide bond; Lissencephaly; Methylation; Microtubule; Nitration; Nucleotide-binding; Phosphoprotein; Polymorphism; Reference proteome
1 P68363 TUBA1B Tubulin alpha-1B chain 451 3D-structure; Acetylation; Alternative splicing; Cytoplasm; Cytoskeleton; Direct protein sequencing; GTP-binding; Isopeptide bond; Methylation; Microtubule; Nitration; Nucleotide-binding; Phosphoprotein; Reference proteome; Ubl conjugation
1 Q13748 TUBA3C Tubulin alpha-3C chain 450 Acetylation; Alternative splicing; Cytoplasm; Cytoskeleton; GTP-binding; Isopeptide bond; Methylation; Microtubule; Nitration; Nucleotide-binding; Phosphoprotein; Polymorphism; Reference proteome
6 P68366 TUBA4A Tubulin alpha-4A chain 448 Acetylation; Alternative splicing; Amyotrophic lateral sclerosis; Cytoplasm; Cytoskeleton; Direct protein sequencing; GTP-binding; Methylation; Microtubule; Neurodegeneration; Nitration; Nucleotide-binding; Phosphoprotein; Reference proteome
1 Q9NY65 TUBA8 Tubulin alpha-8 chain 449 Alternative splicing; Cytoplasm; Cytoskeleton; GTP-binding; Microtubule; Nucleotide-binding; Polymorphism; Reference proteome
2 P23258 TUBG1 Tubulin gamma-1 chain 451 3D-structure; Cytoplasm; Cytoskeleton; Disease mutation; GTP-binding; Lissencephaly; Microtubule; Nucleotide-binding; Phosphoprotein; Polymorphism; Reference proteome
2 Q9BSJ2 TUBGCP2 Gamma-tubulin complex component 2 902 3D-structure; Alternative splicing; Cytoplasm; Cytoskeleton; Microtubule; Phosphoprotein; Polymorphism; Reference proteome
1 Q9UGJ1 TUBGCP4 Gamma-tubulin complex component 4 667 3D-structure; Alternative splicing; Cytoplasm; Cytoskeleton; Direct protein sequencing; Mental retardation; Microtubule; Primary microcephaly; Reference proteome
2 O15042 U2SURP U2 snRNP-associated SURP motif-containing protein 1029 Acetylation; Alternative splicing; Coiled coil; Isopeptide bond; Nucleus; Phosphoprotein; RNA-binding; Reference proteome; Ubl conjugation
2 P62988 UBB Polyubiquitin-B [Cleaved into: Ubiquitin] 229 3D-structure; ADP-ribosylation; Cytoplasm; Direct protein sequencing; Isopeptide bond; Nucleus; Phosphoprotein; Reference proteome; Repeat; Ubl conjugation
User defined Q5U5U6 UBB Epididymis secretory protein Li 50 229
2 Q15386 UBE3C Ubiquitin-protein ligase E3C 1083 3D-structure; Alternative splicing; Direct protein sequencing; Nucleus; Proteasome; Reference proteome; Transferase; Ubl conjugation pathway
2 Q8IWV8 UBR2 E3 ubiquitin-protein ligase UBR2 1755 3D-structure; Acetylation; Alternative splicing; Coiled coil; Metal-binding; Nucleus; Polymorphism; Reference proteome; Transferase; Ubl conjugation pathway; Zinc; Zinc-finger
1 Q9H3U1 UNC45A Protein unc-45 homolog A 944 3D-structure; Acetylation; Alternative splicing; Chaperone; Cytoplasm; Developmental protein; Differentiation; Myogenesis; Nucleus; Phosphoprotein; Polymorphism; Reference proteome; Repeat; TPR repeat
1 Q8TED0 UTP15 U3 small nucleolar RNA-associated protein 15 homolog 518 Acetylation; Alternative splicing; Isopeptide bond; Nucleus; Polymorphism; Reference proteome; Repeat; Ribosome biogenesis; Transcription; Transcription regulation; Ubl conjugation; WD repeat; rRNA processing
1 P61964 WDR5 WD repeat-containing protein 5 334 3D-structure; Acetylation; Chromatin regulator; Disease mutation; Isopeptide bond; Nucleus; Reference proteome; Repeat; Transcription; Transcription regulation; Ubl conjugation; WD repeat
2 Q9BQA1 WDR77 Methylosome protein 50 342 3D-structure; Alternative splicing; Cytoplasm; Direct protein sequencing; Nucleus; Phosphoprotein; Polymorphism; Reference proteome; Repeat; WD repeat
2 O14980 XPO1 Exportin-1 1071 3D-structure; Acetylation; Cytoplasm; Direct protein sequencing; Host-virus interaction; mRNA transport; Nucleus; Phosphoprotein; Protein transport; Reference proteome; Repeat; RNA-binding; Transport;
2 Q9HAV4 XPO5 Exportin-5 1204 3D-structure; Acetylation; Cytoplasm; Direct protein sequencing; Host-virus interaction; Nucleus; Phosphoprotein; Polymorphism; Protein transport; RNA-binding; RNA-mediated gene silencing; Reference proteome; Transport; tRNA-binding
1 Q9UIA9 XPO7 Exportin-7 1087 Acetylation; Cytoplasm; Direct protein sequencing; Nucleus; Phosphoprotein; Polymorphism; Protein transport; Reference proteome; Transport
2 O43592 XPOT Exportin-T 962 Acetylation; Cytoplasm; Direct protein sequencing; Nucleus; Polymorphism; RNA-binding; Reference proteome; Transport; tRNA-binding
2 P13010 XRCC5 X-ray repair cross-complementing protein 5 732 3D-structure; ADP-ribosylation; ATP-binding; Acetylation; Activator; Chromosome; DNA damage; DNA recombination; DNA repair; DNA-binding; Direct protein sequencing; Helicase; Host-virus interaction; Hydrolase; Immunity; Innate immunity; Isopeptide bond; Nucleotide-binding; Nucleus; Phosphoprotein; Polymorphism; Reference proteome; Ribosome biogenesis; Systemic lupus erythematosus; Transcription; Transcription regulation; Ubl conjugation
4 P12956 XRCC6 X-ray repair cross-complementing protein 6 609 3D-structure; ADP-ribosylation; ATP-binding; Acetylation; Activator; Alternative splicing; Chromosome; DNA damage; DNA recombination; DNA repair; DNA-binding; Direct protein sequencing; Helicase; Host-virus interaction; Hydrolase; Immunity; Innate immunity; Isopeptide bond; Lyase; Multifunctional enzyme; Nucleotide-binding; Nucleus; Phosphoprotein; Reference proteome; Systemic lupus erythematosus; Transcription; Transcription regulation; Ubl conjugation
2 Q8IZH2 XRN1 5'-3' exoribonuclease 1 1706 Alternative splicing; Cytoplasm; DNA-binding; Exonuclease; Hydrolase; Nuclease; Phosphoprotein; Polymorphism; RNA-binding; Reference proteome; Tumor suppressor
2 P31946 YWHAB 14-3-3 protein beta/alpha 246 3D-structure; Acetylation; Alternative initiation; Cytoplasm; Direct protein sequencing; Host-virus interaction; Isopeptide bond; Membrane; Nitration; Phosphoprotein; Polymorphism; Reference proteome; Ubl conjugation; Vacuole
2 P62258 YWHAE 14-3-3 protein epsilon 255 3D-structure; Acetylation; Alternative splicing; Cytoplasm; Direct protein sequencing; Host-virus interaction; Isopeptide bond; Nucleus; Phosphoprotein; Reference proteome; Ubl conjugation
2 P27348 YWHAQ 14-3-3 protein theta 245 3D-structure; Acetylation; Cytoplasm; Direct protein sequencing; Isopeptide bond; Nitration; Phosphoprotein; Reference proteome; Ubl conjugation
1 P25490 YY1 Transcriptional repressor protein YY1 414 3D-structure; ADP-ribosylation; Activator; DNA damage; DNA recombination; DNA repair; DNA-binding; Differentiation; Direct protein sequencing; Disease mutation; Isopeptide bond; Mental retardation; Metal-binding; Nucleus; Phosphoprotein; Polymorphism; Reference proteome; Repeat; Repressor; Spermatogenesis; Transcription; Transcription regulation; Ubl conjugation; Zinc; Zinc-finger
2 Q13105 ZBTB17 Zinc finger and BTB domain-containing protein 17 803 3D-structure; Alternative splicing; DNA-binding; Developmental protein; Isopeptide bond; Metal-binding; Nucleus; Phosphoprotein; Reference proteome; Repeat; Transcription; Transcription regulation; Ubl conjugation; Zinc; Zinc-finger
3 P58317 ZNF121 Zinc finger protein 121 390 DNA-binding; Metal-binding; Nucleus; Reference proteome; Repeat; Transcription; Transcription regulation; Zinc; Zinc-finger
2 Q9Y2X9 ZNF281 Zinc finger protein 281 895 Alternative splicing; DNA-binding; Differentiation; Isopeptide bond; Metal-binding; Nucleus; Phosphoprotein; Polymorphism; Reference proteome; Repeat; Repressor; Transcription; Transcription regulation; Ubl conjugation; Zinc; Zinc-finger