Network Sialic acid pathway_ver2 (61 proteins, 56 interactions, 3 user-defined )

Network for query 10 proteins

⇒ Interactors (8) of the query protein: NAGK (Q9UJ70)

⇒ Interactors (1) of the query protein: GNPNAT1 (Q96EK6)

⇒ Interactors (2) of the query protein: RENBP (P51606)

⇒ Interactors (0) of the query protein: (O95394)

⇒ Interactors (0) of the query protein: (Q16222)

⇒ Interactors (4) of the query protein: GNE (Q9Y223)

⇒ Interactors (40) of the query protein: NANS (Q9NR45)

⇒ Interactors (0) of the query protein: (Q9BXD5)

⇒ Interactors (0) of the query protein: (Q8TBE9)

⇒ Interactors (1) of the query protein: CMAS (Q8NFW8)

Interactors(8) of the protein: NAGK (Q9UJ70 )

Interaction detail	UniProt AC	Gene name	Protein name	Protein length	Keywords
2	Q5M9N0	CCDC158	Coiled-coil domain-containing protein 158	1113	Alternative splicing; Coiled coil; Polymorphism; Reference proteome
1	Q9UI36	DACH1	Dachshund homolog 1	758	3D-structure; Activator; Alternative splicing; Coiled coil; DNA-binding; Developmental protein; Nucleus; Phosphoprotein; Polymorphism; Reference proteome; Repressor; Transcription; Transcription regulation
1	Q8IU60	DCP2	m7GpppN-mRNA hydrolase	420	3D-structure; Alternative splicing; Cytoplasm; Hydrolase; Manganese; Metal-binding; Nonsense-mediated mRNA decay; Nucleus; Phosphoprotein; Polymorphism; RNA-binding; Reference proteome
1	Q8TBB1	LNX1	E3 ubiquitin-protein ligase LNX	728	3D-structure; Alternative splicing; Cytoplasm; Metal-binding; Phosphoprotein; Reference proteome; Repeat; Transferase; Ubl conjugation pathway; Zinc; Zinc-finger
1	O95777	LSM8	U6 snRNA-associated Sm-like protein LSm8	96	3D-structure; Acetylation; Direct protein sequencing; Nucleus; RNA-binding; Reference proteome; Ribonucleoprotein; Spliceosome; mRNA processing; mRNA splicing
1	Q15796	SMAD2	Mothers against decapentaplegic homolog 2	467	3D-structure; Acetylation; Alternative splicing; Cytoplasm; DNA-binding; Direct protein sequencing; Metal-binding; Nucleus; Phosphoprotein; Polymorphism; Reference proteome; Transcription; Transcription regulation; Ubl conjugation; Zinc
1	O15198	SMAD9	Mothers against decapentaplegic homolog 9	467	3D-structure; Alternative splicing; Cytoplasm; DNA-binding; Disease mutation; Metal-binding; Nucleus; Phosphoprotein; Reference proteome; Transcription; Transcription regulation; Zinc
1	O75716	STK16	Serine/threonine-protein kinase 16	305	3D-structure; ATP-binding; Cytoplasm; Kinase; Lipoprotein; Membrane; Myristate; Nucleotide-binding; Palmitate; Phosphoprotein; Polymorphism; Reference proteome; Serine/threonine-protein kinase; Transferase

Interactors(1) of the protein: GNPNAT1 (Q96EK6 )

Interaction detail	UniProt AC	Gene name	Protein name	Protein length	Keywords
User defined	Q96EK6	GNPNAT1	Glucosamine 6-phosphate N-acetyltransferase	184	3D-structure; Acyltransferase; Endosome; Golgi apparatus; Membrane; Reference proteome; Transferase

Interactors(2) of the protein: RENBP (P51606 )

Interaction detail	UniProt AC	Gene name	Protein name	Protein length	Keywords
1	P00797	REN	Renin	406	3D-structure; Alternative splicing; Aspartyl protease; Cleavage on pair of basic residues; Direct protein sequencing; Disease mutation; Disulfide bond; Glycoprotein; Hydrolase; Membrane; Polymorphism; Protease; Reference proteome; Secreted; Signal; Zymogen
1	O96006	ZBED1	Zinc finger BED domain-containing protein 1	694	3D-structure; DNA-binding; Metal-binding; Nucleus; Reference proteome; Zinc; Zinc-finger

Interactors(0) of the protein: (O95394 )

Interactors(0) of the protein: (Q16222 )

Interactors(4) of the protein: GNE (Q9Y223 )

Interaction detail	UniProt AC	Gene name	Protein name	Protein length	Keywords
1	Q14194	CRMP1	Dihydropyrimidinase-related protein 1	572	3D-structure; Alternative splicing; Cell projection; Cytoplasm; Cytoskeleton; Direct protein sequencing; Nitration; Phosphoprotein; Polymorphism; Reference proteome
User defined	Q9HCM3	KIAA1549	UPF0606 protein KIAA1549	1950	Alternative promoter usage; Alternative splicing; Cell projection; Chromosomal rearrangement; Membrane; Phosphoprotein; Polymorphism; Reference proteome; Retinitis pigmentosa; Transmembrane; Transmembrane helix
1	Q5UIP0	RIF1	Telomere-associated protein RIF1	2472	Alternative splicing; Cell cycle; Chromosome; Cytoplasm; Cytoskeleton; DNA damage; DNA repair; Nucleus; Phosphoprotein; Polymorphism; Reference proteome; Telomere
1	Q05516	ZBTB16	Zinc finger and BTB domain-containing protein 16	673	3D-structure; Alternative splicing; Chromosomal rearrangement; DNA-binding; Disease mutation; Mental retardation; Metal-binding; Nucleus; Phosphoprotein; Proto-oncogene; Reference proteome; Repeat; Repressor; Transcription; Transcription regulation; Ubl conjugation pathway; Zinc; Zinc-finger

Interactors(40) of the protein: NANS (Q9NR45 )

Interaction detail	UniProt AC	Gene name	Protein name	Protein length	Keywords
User defined	A8K7X4	A8K7X4	A8K7X4
13	P49588	AARS1	Alanine--tRNA ligase, cytoplasmic	968	3D-structure; ATP-binding; Acetylation; Alternative splicing; Aminoacyl-tRNA synthetase; Charcot-Marie-Tooth disease; Cytoplasm; Direct protein sequencing; Disease mutation; Epilepsy; Ligase; Metal-binding; Neurodegeneration; Neuropathy; Nucleotide-binding; Phosphoprotein; Polymorphism; Protein biosynthesis; RNA-binding; Reference proteome; Ubl conjugation; Zinc; tRNA-binding
13	P63261	ACTG1	Actin, cytoplasmic 2	375	3D-structure; ATP-binding; Acetylation; Cytoplasm; Cytoskeleton; Deafness; Direct protein sequencing; Disease mutation; Isopeptide bond; Mental retardation; Methylation; Non-syndromic deafness; Nucleotide-binding; Oxidation; Polymorphism; Reference proteome
13	P12814	ACTN1	Alpha-actinin-1	892	3D-structure; Acetylation; Actin-binding; Alternative splicing; Calcium; Cell junction; Cell membrane; Cell projection; Cytoplasm; Cytoskeleton; Direct protein sequencing; Disease mutation; Membrane; Metal-binding; Phosphoprotein; Polymorphism; Reference proteome; Repeat
13	P04075	ALDOA	Fructose-bisphosphate aldolase A	364	3D-structure; Acetylation; Alternative splicing; Cytoplasm; Direct protein sequencing; Disease mutation; Glycogen storage disease; Glycolysis; Hereditary hemolytic anemia; Hydroxylation; Isopeptide bond; Lyase; Phosphoprotein; Polymorphism; Reference proteome; Schiff base; Ubl conjugation
13	P13639	EEF2	Elongation factor 2	858	3D-structure; ADP-ribosylation; Acetylation; Cytoplasm; Direct protein sequencing; Disease mutation; Elongation factor; GTP-binding; Isopeptide bond; Methylation; Neurodegeneration; Nucleotide-binding; Nucleus; Phosphoprotein; Protein biosynthesis; Reference proteome; Spinocerebellar ataxia; Ubl conjugation
13	O15372	EIF3H	Eukaryotic translation initiation factor 3 subunit H	352	3D-structure; Cytoplasm; Initiation factor; Isopeptide bond; Phosphoprotein; Protein biosynthesis; Reference proteome; Ubl conjugation
13	P49327	FASN	Fatty acid synthase	2511	3D-structure; Acetylation; Cytoplasm; Direct protein sequencing; Fatty acid biosynthesis; Fatty acid metabolism; Hydrolase; Isopeptide bond; Lipid biosynthesis; Lipid metabolism; Lyase; Multifunctional enzyme; NAD; NADP; Oxidoreductase; Phosphopantetheine; Phosphoprotein; Polymorphism; Pyridoxal phosphate; Reference proteome; Transferase; Ubl conjugation
13	P21333	FLNA	Filamin-A	2647	3D-structure; Acetylation; Actin-binding; Alternative splicing; Cell projection; Cilium biogenesis/degradation; Cytoplasm; Cytoskeleton; Deafness; Direct protein sequencing; Disease variant; Isopeptide bond; Phosphoprotein; Reference proteome; Repeat; Ubl conjugation;
13	P04406	GAPDH	Glyceraldehyde-3-phosphate dehydrogenase	335	3D-structure; ADP-ribosylation; Acetylation; Alternative splicing; Apoptosis; Cytoplasm; Cytoskeleton; Direct protein sequencing; Glycolysis; Isopeptide bond; Membrane; Methylation; NAD; Nucleus; Oxidation; Oxidoreductase; Phosphoprotein; Polymorphism; Reference proteome; S-nitrosylation; Transferase; Translation regulation; Ubl conjugation
13	P04899	GNAI2	Guanine nucleotide-binding protein G	355	3D-structure; ADP-ribosylation; Alternative splicing; Cell cycle; Cell division; Cell membrane; Cytoplasm; Cytoskeleton; GTP-binding; Lipoprotein; Magnesium; Membrane; Metal-binding; Myristate; Nucleotide-binding; Palmitate; Reference proteome; Transducer
15	P08238	HSP90AB1	Heat shock protein HSP 90-beta	724	3D-structure; Acetylation; ATP-binding; Cell membrane; Chaperone; Cytoplasm; Direct protein sequencing; Glycoprotein; Membrane; Methylation; Nucleotide-binding; Nucleus; Phosphoprotein; Reference proteome; S-nitrosylation; Secreted; Stress response; Ubl conjugation;
13	A8K5I0	HSPA1B	Epididymis secretory protein Li 103	641	ATP-binding; Coiled coil; Nucleotide-binding; Stress response
13	Q92598	HSPH1	Heat shock protein 105 kDa	858	3D-structure; ATP-binding; Acetylation; Alternative splicing; Cytoplasm; Direct protein sequencing; Nucleotide-binding; Phosphoprotein; Reference proteome; Stress response
13	Q9NSE4	IARS2	Isoleucine--tRNA ligase, mitochondrial	1012	ATP-binding; Acetylation; Aminoacyl-tRNA synthetase; Cataract; Deafness; Disease mutation; Ligase; Mitochondrion; Neuropathy; Nucleotide-binding; Polymorphism; Protein biosynthesis; Reference proteome; Transit peptide
13	P00338	LDHA	L-lactate dehydrogenase A chain	332	3D-structure; Acetylation; Alternative splicing; Cytoplasm; Direct protein sequencing; Disease mutation; Glycogen storage disease; Isopeptide bond; NAD; Oxidoreductase; Phosphoprotein; Polymorphism; Reference proteome; Ubl conjugation
13	P40925	MDH1	Malate dehydrogenase, cytoplasmic	334	Acetylation; Alternative splicing; Cytoplasm; Direct protein sequencing; Methylation; NAD; Oxidoreductase; Phosphoprotein; Reference proteome; Tricarboxylic acid cycle; Ubl conjugation
13	P11586	MTHFD1	C-1-tetrahydrofolate synthase, cytoplasmic	935	3D-structure; ATP-binding; Acetylation; Amino-acid biosynthesis; Cytoplasm; Direct protein sequencing; Disease mutation; Histidine biosynthesis; Hydrolase; Ligase; Methionine biosynthesis; Multifunctional enzyme; NADP; Nucleotide-binding; One-carbon metabolism; Oxidoreductase; Phosphoprotein; Polymorphism; Purine biosynthesis; Reference proteome
13	Q9HB07	MYG1	MYG1 exonuclease	376	Acetylation; Hydrolase; Mitochondrion; Nuclease; Nucleus; Phosphoprotein; Polymorphism; Reference proteome; Transit peptide
13	P35579	MYH9	Myosin-9	1960	3D-structure; ATP-binding; Acetylation; Actin-binding; Alport syndrome; Alternative splicing; Calmodulin-binding; Cataract; Cell adhesion; Cell shape; Coiled coil; Cytoplasm; Cytoskeleton; Deafness; Direct protein sequencing; Disease mutation; Methylation; Motor protein; Myosin; Non-syndromic deafness; Nucleotide-binding; Phosphoprotein; Polymorphism; Reference proteome; Ubl conjugation
13	Q14980	NUMA1	Nuclear mitotic apparatus protein 1	2115	3D-structure; ADP-ribosylation; Acetylation; Alternative splicing; Cell cycle; Cell division; Cell membrane; Chromosome; Chromosome partition; Coiled coil; Cytoplasm; Cytoskeleton; Glycoprotein; Isopeptide bond; Lipid-binding; Lipoprotein; Membrane; Microtubule; Mitosis; Nucleus; Phosphoprotein; Polymorphism; Reference proteome; Ubl conjugation
13	P00558	PGK1	Phosphoglycerate kinase 1	417	3D-structure; ATP-binding; Acetylation; Alternative splicing; Cytoplasm; Direct protein sequencing; Disease mutation; Glycolysis; Hereditary hemolytic anemia; Hydroxylation; Kinase; Nucleotide-binding; Phosphoprotein; Polymorphism; Reference proteome; Transferase
14	P14618	PKM	Pyruvate kinase PKM	531	3D-structure; Acetylation; Allosteric enzyme; Alternative splicing; ATP-binding; Cytoplasm; Direct protein sequencing; Glycolysis; Hydroxylation; Isopeptide bond; Kinase; Magnesium; Metal-binding; Methylation; Nucleotide-binding; Nucleus; Phosphoprotein; Potassium; Pyruvate; Reference proteome; Transferase; Translation regulation; Ubl conjugation;
13	P78527	PRKDC	DNA-dependent protein kinase catalytic subunit	4128	3D-structure; ATP-binding; Acetylation; Alternative splicing; Biological rhythms; DNA damage; DNA recombination; DNA repair; DNA-binding; Disease mutation; Immunity; Innate immunity; Kinase; Nucleotide-binding; Nucleus; Phosphoprotein; Polymorphism; Reference proteome; Repeat; Ribosome biogenesis; SCID; Serine/threonine-protein kinase; TPR repeat; Transferase; Ubl conjugation
13	Q9Y617	PSAT1	Phosphoserine aminotransferase	370	3D-structure; Acetylation; Alternative splicing; Amino-acid biosynthesis; Aminotransferase; Disease mutation; Phosphoprotein; Polymorphism; Pyridoxal phosphate; Reference proteome; Serine biosynthesis; Transferase
13	P28074	PSMB5	Proteasome subunit beta type-5	263	3D-structure; Alternative splicing; Cytoplasm; Direct protein sequencing; Host-virus interaction; Hydrolase; Nucleus; Protease; Proteasome; Reference proteome; Threonine protease; Zymogen;
13	Q99460	PSMD1	26S proteasome non-ATPase regulatory subunit 1	953	3D-structure; Acetylation; Alternative splicing; Phosphoprotein; Proteasome; Reference proteome; Repeat;
13	P46777	RPL5	60S ribosomal protein L5	297	3D-structure; Acetylation; Cytoplasm; Diamond-Blackfan anemia; Direct protein sequencing; Disease mutation; Isopeptide bond; Nucleus; Phosphoprotein; Polymorphism; RNA-binding; Reference proteome; Ribonucleoprotein; Ribosomal protein; Ubl conjugation; rRNA-binding
13	P18124	RPL7	60S ribosomal protein L7	248	3D-structure; Acetylation; Direct protein sequencing; Phosphoprotein; RNA-binding; Reference proteome; Repeat; Ribonucleoprotein; Ribosomal protein
13	P05388	RPLP0	60S acidic ribosomal protein P0	317	3D-structure; Alternative splicing; Cytoplasm; Direct protein sequencing; Isopeptide bond; Nucleus; Phosphoprotein; Reference proteome; Ribonucleoprotein; Ribosomal protein; Ubl conjugation
13	P61247	RPS3A	40S ribosomal protein S3a	264	3D-structure; Acetylation; Cytoplasm; Differentiation; Direct protein sequencing; Isopeptide bond; Nucleus; Phosphoprotein; Reference proteome; Ribonucleoprotein; Ribosomal protein; Ubl conjugation
13	P62701	RPS4X	40S ribosomal protein S4, X isoform	263	3D-structure; Acetylation; Cytoplasm; Direct protein sequencing; Isopeptide bond; RNA-binding; Reference proteome; Ribonucleoprotein; Ribosomal protein; Ubl conjugation; rRNA-binding
13	P62753	RPS6	40S ribosomal protein S6	249	3D-structure; Acetylation; Direct protein sequencing; Hydroxylation; Isopeptide bond; Phosphoprotein; Polymorphism; Reference proteome; Ribonucleoprotein; Ribosomal protein; Ubl conjugation
13	P08865	RPSA	40S ribosomal protein SA	295	3D-structure; Acetylation; Cell membrane; Cytoplasm; Direct protein sequencing; Disease mutation; Host cell receptor for virus entry; Host-virus interaction; Isopeptide bond; Membrane; Nucleus; Phosphoprotein; Polymorphism; Receptor; Reference proteome; Repeat; Ribonucleoprotein; Ribosomal protein; Ubl conjugation
13	Q13813	SPTAN1	Spectrin alpha chain, non-erythrocytic 1	2472	3D-structure; Acetylation; Actin capping; Actin-binding; Alternative splicing; Calcium; Calmodulin-binding; Cytoplasm; Cytoskeleton; Direct protein sequencing; Disease mutation; Epilepsy; Mental retardation; Metal-binding; Phosphoprotein; Polymorphism; Reference proteome; Repeat; SH3 domain
13	P17987	TCP1	T-complex protein 1 subunit alpha	556	3D-structure; ATP-binding; Acetylation; Chaperone; Cytoplasm; Cytoskeleton; Direct protein sequencing; Nucleotide-binding; Phosphoprotein; Polymorphism; Reference proteome
1	Q9UKE5	TNIK	TRAF2 and NCK-interacting protein kinase	1360	3D-structure; ATP-binding; Alternative splicing; Cytoplasm; Cytoskeleton; Endosome; Kinase; Mental retardation; Neurogenesis; Nucleotide-binding; Nucleus; Phosphoprotein; Polymorphism; Reference proteome; Serine/threonine-protein kinase; Transferase; Wnt signaling pathway
13	P06753	TPM3	Tropomyosin alpha-3 chain	285	3D-structure; Acetylation; Actin-binding; Alternative splicing; Chromosomal rearrangement; Coiled coil; Cytoplasm; Cytoskeleton; Direct protein sequencing; Disease mutation; Muscle protein; Nemaline myopathy; Phosphoprotein; Proto-oncogene; Reference proteome
13	P22314	UBA1	Ubiquitin-like modifier-activating enzyme 1	1058	3D-structure; ATP-binding; Acetylation; Alternative initiation; Cytoplasm; Direct protein sequencing; Disease mutation; Ligase; Mitochondrion; Neurodegeneration; Nucleotide-binding; Nucleus; Phosphoprotein; Polymorphism; Reference proteome; Repeat; Ubl conjugation; Ubl conjugation pathway
13	O14980	XPO1	Exportin-1	1071	3D-structure; Acetylation; Cytoplasm; Direct protein sequencing; Host-virus interaction; Nucleus; Phosphoprotein; Protein transport; RNA-binding; Reference proteome; Repeat; Transport; mRNA transport

Interactors(0) of the protein: (Q9BXD5 )

Interactors(0) of the protein: (Q8TBE9 )

Interactors(1) of the protein: CMAS (Q8NFW8 )

Interaction detail	UniProt AC	Gene name	Protein name	Protein length	Keywords
1	Q96PQ1	SIGLEC12	Sialic acid-binding Ig-like lectin 12	595	Alternative splicing; Cell adhesion; Disulfide bond; Glycoprotein; Immunoglobulin domain; Lectin; Membrane; Phosphoprotein; Polymorphism; Reference proteome; Repeat; Signal; Transmembrane; Transmembrane helix