I. Rooman

Latest

• ROBO2 is a stroma suppressor gene in the pancreas and acts via TGF-beta signalling
• Hypermutation In Pancreatic Cancer
• Whole-genome landscape of pancreatic neuroendocrine tumours
• Genomic analyses identify molecular subtypes of pancreatic cancer
• Sirtuin 1 stimulates the proliferation and the expression of glycolysis genes in pancreatic neoplastic lesions
• Pancreas-Specific Sirt1-Deficiency in Mice Compromises Beta-Cell Function without Development of Hyperglycemia
• SOX9 regulates ERBB signalling in pancreatic cancer development
• Whole genomes redefine the mutational landscape of pancreatic cancer
• Genome-wide DNA methylation patterns in pancreatic ductal adenocarcinoma reveal epigenetic deregulation of SLIT-ROBO, ITGA2 and MET signaling
• Clinical and molecular characterization of HER2 amplified-pancreatic cancer
• Histomolecular phenotypes and outcome in adenocarcinoma of the ampulla of vater
• Sirtuin-1 regulates acinar-to-ductal metaplasia and supports cancer cell viability in pancreatic cancer
• Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes