We present NUWA, a computational pipeline for robust inference of protein abundances missing in mass spectrometry proteomic profiles. By leveraging information borrowed from neighbor proteins across cohort profiles, NUWA-ms exhibits superior performance with non-random and precise inference among multi-metric evaluation, and its application could lead to improved performance of versatile downstream analyses using proteomic profiles.
Please visit the NUWA-ms web server for a quick start, while the NUWA R package is available on GitHub for users needing local large-scale analysis without number limit and full functions.
