Research

Pharmacogenomic profiling of intra-tumor heterogeneity of liver cancer organoids

Inter- and intra-tumor heterogeneity is a major hurdle in primary liver cancer (PLC) precision therapy. In collaboration with Prof. …

Dual roles of Beta-arrestin 1 in mediating cell metabolism and proliferation

β-Arrestin 1 (ARRB1) has been known as a key negative regulator of G protein-coupled receptor signaling. During the past decade, it has …

ReProMSig

We provide the Reproducible Prognosis Molecular Signature platform (ReProMSig), to facilitate biomarker development and applications in …

Quantitative comparison of Matrigel dissolving methods

By integrative analysis of label-free proteomes of Matrigel and SILAC proteomes of organoids collected by three methods respectively, …

Proteogenomic Analysis of Gastric Cancer (GC)

Combining whole exome sequencing, RNA-sequencing, and mass spectrometry-based proteomic profiling to elucidate GC molecular landscape.

Analysis of GC intratumor heterogeneity

Applying multi-region whole-exome sequencing and organoid modelling to decode GC intratumor heterogeneity.

GPGC

ICGC-ARGO Project: Genomic and Proteomic Characterisation of Gastric Cancer.

PINA 3.0

An integrated platform for protein interaction network construction, filtering, analysis, visualization and cancer-context annotation.

CVCDAP

A powerful Cancer Virtual Cohort Discovery Analysis Platform with large cancer datasets integrated.

Members

Director

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Jianmin Wu

Director,
Center for Cancer Bioinformatics

Member,
ICGC-ARGO Scientific Planning Committee

Staff

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Lihua Cao

Research Staff

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Yang Du

Research Staff

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Man Wang

Research Staff

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Jiale Chen

Research Staff

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Chenyu Guo

Research Staff

Grad Students

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Zirui Li

PhD student (2024-)

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Xinya Peng

Master student (2023-)

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Yixuan Shu

Master student (2021-)

Alumni

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Yanru Hai

Master student (2019-2022)

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Huan Yu

Ph.D (2018-2022)

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Ting Zhang

Research assistant

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Tingting Zhao

Ph.D (2019-2022)

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Yuhao Xie

Master student (2018-2021) , co-supervised with Dr. Ence Yang

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Yang Yang

Research Staff

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Meng Cai

Master Student(2018 - 2021), co-supervised with Dr. Ence Yang

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Xiaoqing Guan

Ph.D (2017-2020), co-supervised with Prof. Jiafu Ji

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Yu Cai

Master student (2017-2020)

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Sijia Cui

Research Staff

Recent News

Our recent work analyzing multi-region organoids reveal inter- and intra-tumor pharmacogenomic heterogeneity in primary liver cancer, in collaberation with Prof. Zhang Ning. Please read the article published in Cancer Cell for more details.

ReProMSig (Reproducible Prognosis Molecular Signature) has been online at Briefings in Bioinformatics. Congratulations to Tingting Zhao and Lihua Cao!

We are excited to be a part of a Lancet Oncology Commission focusing on cancer genomics and precision oncology. This new commission will be coordinated by the International Cancer Genome Consortium Accelerating Research in Genomic Oncology (ICGC-ARGO) initiative, and bring together international experts with relevant expertise across a range of fields, to offer practical solutions for key challenges in ensuring sustainable and equitable access to omics testing and a blueprint for advancing cancer diagnosis and treatment.

Join Us

Open positions for research faculty and students

Open positions

Contact

  • +86-10-88196986
  • Peking University Cancer Hospital & Institute, 52 Fu-Cheng Road, Hai-Dian District, Beijing 100142, China
    北京市海淀区阜成路52号,北京大学肿瘤医院 西门科研楼608-2室